DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment POSH and gei-18

DIOPT Version :9

Sequence 1:	NP_523776.1	Gene:	POSH / 36990	FlyBaseID:	FBgn0040294	Length:	838	Species:	Drosophila melanogaster
Sequence 2:	NP_502681.3	Gene:	gei-18 / 178357	WormBaseID:	WBGene00001575	Length:	304	Species:	Caenorhabditis elegans

Alignment Length:	164	Identity:	32/164 - (19%)
Similarity:	56/164 - (34%)	Gaps:	55/164 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   478 LRARDQQQLMHQWKYVP---------------------QNADA-------------QMAQVQQHP 508
            ||...:|..:|..::.|                     ||:.:             |:.:.:.|.
Worm   142 LRLIGEQMFLHPDEHAPLVIVIAGLKANEFSEKLNKAIQNSKSETNSNNLPIEIGNQLERGELHA 206

  Fly   509 VAPDVRLNNMLSMQPPDLPPRQQQATATTTSCSVWSK--PVEALFSRKSEPKPET------ATAS 565
            :     |||.|:.|   :.||  .|..|......|..  .:.|.....:.|.|:|      :|..
Worm   207 I-----LNNALASQ---MTPR--TAVLTNIDLLAWDAVLVLHAFADHGTFPIPKTVLLLAVSTEE 261

  Fly   566 TTSSSSSGAVGLMRRLTHMKTRSKSPGASLQQVP 599
            ||.|.:|....:::.:|:   |....|.:...:|
Worm   262 TTYSGNSCDGKILKLVTN---RWIENGGNYDNIP 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
POSH	NP_523776.1	RING	11..53	CDD:238093
		SH3	139..191	CDD:302595
		SH3_SH3RF_2	199..251	CDD:212721
		SH3_SH3RF_3	424..477	CDD:212717
		SH3_SH3RF_C	782..836	CDD:212719
gei-18	NP_502681.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2995
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900