Protein Alignment Ns2 and gnl3l

DIOPT Version :10

• Sequence 1: NP_611232.1
• Gene: Ns2 / 36989
• FlyBaseID: FBgn0034243
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001002875.1
• Gene: gnl3l / 442932
• ZFINID: ZDB-GENE-040723-1
• Length: 565
• Species: Danio rerio
• Alignment Length: 522
• Identity: 147/522 - (28%)
• Similarity: 241/522 - (46%)
• Gaps: 111/522 - (21%)

  Fly   152 KKQRKRVSLKVRDLEDLSKAADDQADKYDSAKDLDLIREDTGEKKAV------RDWVFGAGQSKR 210
            :::|:|:|   |:.|.:.:.:   .|.|.  ||:.| |:...|::.:      :...|....|::
Zfish    58 QQERQRLS---REKEMMKRRS---LDSYQ--KDIQL-RQREFEQREIQMQNLEKHVNFETENSRK 113

  Fly   211 IW-NELHKVVDASDVLLQVLDARDPMGTRSKYIEEFLRKEKPHKHLFFILNKVDLVPVWVTQRWV 274
            .: .|..||::|:||:|:|||||||:|.|...:|:.:.:...:|.:..:|||:|||...:.::|:
Zfish   114 AYCREFKKVIEAADVILEVLDARDPLGCRCPQVEQAVVQSGTNKKIVLVLNKIDLVSKDIVEKWI 178

  Fly   275 AILSAEYPTIAFHASLQHP------------------------FGKGALINLFRQLGKLHLDKKQ 315
            ..|..|:||:||.:|.|..                        .|...|:.|.....:....|..
Zfish   179 KYLRNEFPTVAFKSSTQQQNKNLKRSRVPVTQATQELLESSACVGADCLMKLLGNYCRNQDIKTA 243

  Fly   316 ISVGFIGYPNVGKSSVINALRSKKVCKVAPIAGETKVWQYITLMKRIFLIDCPGVVYPTAETDTE 380
            |:||.:|:|||||||:||:|:..:.|.|....|.||..|.:.|.|.|.|:||||:|..|:.:|..
Zfish   244 ITVGVVGFPNVGKSSLINSLKRARACNVGATPGVTKCLQEVHLDKHIKLLDCPGIVMATSTSDAA 308

  Fly   381 KVLKGVVRVELVTNPEDYVDSLLKRVRPEYISKNYKIEHWNTSTHFLEQLAQKTGKLLKGGEPDV 445
            .:|:..|::|.:.:|...|:::|:|.....|..:|.|..:.|:..||..||::.|||.|||.||.
Zfish   309 MILRNCVKIEQLVDPLPAVEAILRRCNKMQIIDHYGIPDFQTAHEFLALLARRQGKLRKGGLPDS 373

  Fly   446 TVTARMVLNDWQRGKLPFYV-PPE----------------------------------------- 468
            ...|:.||.||..|::.::. |||
Zfish   374 DKAAKSVLMDWTGGRISYFTHPPETHTLPTHVSAEIVAEMGKAFDWDELEKGNLEALAECGTSDV 438

  Fly   469 --GFAVPKS---QEGKEE---EVVAEDPNEDAK----------SEAPTFVSESVKKAREFKQIQD 515
              ||.:..|   |.|:.|   |:..::|.:|.:          .|.|.|...:|    |.|..:.
Zfish   439 QMGFCMATSGLTQGGQGEDLAELQMDEPLDDPELQDKVELMDADEDPEFGPMTV----ELKVPKT 499

  Fly   516 FRKIRVGLEYEQEDVKDLDHIDLELLEQQKAERAAKKK-----ARIHNLGEEDEESSDGADEFYS 575
            ...:...:..:..|:||:  :|::.|.|.:|.:||.||     .|...||.:..:|...|..|..
Zfish   500 KSGVVEAVGPKPVDLKDI--LDIDPLLQGQALQAANKKRKKQQKRADKLGTKLSDSLTAALNFSF 562

  Fly   576 ED 577
            .|
Zfish   563 SD 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns2	NP_611232.1	NGP1NT	49..179	CDD:462379	6/26 (23%)
		NGP_1	214..370	CDD:206751	64/179 (36%)
		PTZ00121	<474..657	CDD:173412	31/125 (25%)
gnl3l	NP_001002875.1	GN3L_Grn1	2..73	CDD:462569	5/17 (29%)
		G_path_suppress	38..>114	CDD:464961	14/64 (22%)
		Nucleostemin_like	127..298	CDD:206753	60/170 (35%)
		P-loop containing Nucleoside Triphosphate Hydrolases	249..357	CDD:476819	41/107 (38%)