Protein Alignment Ns2 and Noa1

DIOPT Version :10

• Sequence 1: NP_611232.1
• Gene: Ns2 / 36989
• FlyBaseID: FBgn0034243
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001388376.1
• Gene: Noa1 / 289562
• RGDID: 1359460
• Length: 694
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 124/648 - (19%)
• Similarity: 190/648 - (29%)
• Gaps: 274/648 - (42%)

  Fly   120 PSQLPVTLLNEAAKYKRVHLLDTESFDSTFGPK----KQRKRVSLKVRDLEDLSKAADDQADKYD 180
            |.:.|...|.|..:.:.:..|..|........:    :|:.|..|:...:.:|..|:...:..|.
  Rat    78 PERTPEEQLRELRELRELQQLQQEKERQRLQRREERLQQKLRAGLRALPVPELPDASVPPSGIYC 142

  Fly   181 SAKDLDLIRED-------TGEKKAVRDWVFGAGQS---------KRIWNELHKVVDASDVLLQVL 229
            |....:|..:.       .|||  .||    |.|:         :|.|..:|   ....:.|||
  Rat   143 SGCGAELHCQHPGLPGYLPGEK--FRD----AAQAEGGLARTVCQRCWLLVH---HRRALRLQV- 197

  Fly   230 DARDPMGTRSKYIE------------------------EFLRKEKPH----KHLFFILNKVDLVP 266
                   :|.:|:|                        :.|..:.|.    |.||.:.|||||:|
  Rat   198 -------SRDQYLELVSTALQRPGPALVLYMVDLLDLPDALLPDLPKLVGPKQLFVLGNKVDLLP 255

  Fly   267 ---VWVTQR-----WVAILSAEYPTIAFHASLQHPFGK--------------------------- 296
               ....||     |...:.|.......|...|:|.|.
  Rat   256 QDAPGYLQRLRKRLWNDCIRAGLVVAPGHRGPQYPTGNEPLDEIKNQNPSSRSRTVVKDVRLISA 320

  Fly   297 ----------GALINLFRQLGKLHLDKKQISVGFIGYPNVGKSSVINALRSKKVC---------- 341
                      .||...:|..|.::|         :|..|.|||::.|.|.....|
  Rat   321 KTGYGVEELISALQRSWRYRGDVYL---------VGTTNAGKSTLFNTLLESDYCTAKGSEAIDR 376

  Fly   342 -KVAPIAGETKVWQYITLMKRIFLIDCPGVVYPTAETDTEKVLKGVVRVELVTNPEDYVDSLLKR 405
             .::|..|.|     :.|:|           :|                  :.||..|  .:.||
  Rat   377 ATISPWPGTT-----LNLLK-----------FP------------------ICNPTPY--RMFKR 405

  Fly   406 VRPEYISKNYKIEHWNTSTHFLEQLAQKTGKLLKGGEPDVTVTARMVLNDWQRGKLPFYVPPEGF 470
            .:.                  |::.|.||       |.|::...:..||  |..|..:.|...|.
  Rat   406 QKR------------------LQEDASKT-------EEDLSEQEQSQLN--QLKKHGYIVGRVGR 443

  Fly   471 AVPKSQEGKEE---EVVAEDPNEDAKSEAPTFVSESVKKAREFKQIQDFRKIRVGLEYEQEDVKD 532
            ....|::.|||   |..|:....|..:|....|.:|.|:.                |...|||||
  Rat   444 TFLHSRQQKEEVPFEFDADSLAFDMGNEPVVSVRKSTKQT----------------ELTPEDVKD 492

  Fly   533 L-----------DHIDLELLEQQKAE----------RAAKKK----------ARIHNL-GEEDE- 564
            .           ::..|.||.:::.:          |....|          ||:..| |.:..
  Rat   493 AHWFYDTPGITKENCILNLLTEKEIDIVLPTHSIIPRTFVLKPGMVLFLGGIARVDFLQGNQSAW 557

  Fly   565 -------------ESSDGADEFYSEDEYNEDLQRVVHKKAKSKKPQQLAITSSGKFRVAKIQP 614
                         .|.|.||..| |....::|               |.:...||.|:|:..|
  Rat   558 FTVVASNFLPVHISSLDKADALY-EKHAGQEL---------------LLVPMGGKERMAQFPP 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns2	NP_611232.1	NGP1NT	49..179	CDD:462379	11/62 (18%)
		NGP_1	214..370	CDD:206751	44/239 (18%)
		PTZ00121	<474..657	CDD:173412	39/190 (21%)
Noa1	NP_001388376.1	YqeH	180..396	CDD:206748	47/269 (17%)