Protein Alignment MESR4 and ing3

DIOPT Version :9

• Sequence 1: NP_001097359.1
• Gene: MESR4 / 36986
• FlyBaseID: FBgn0034240
• Length: 2171
• Species: Drosophila melanogaster
• Sequence 2: NP_001008672.1
• Gene: ing3 / 493319
• XenbaseID: XB-GENE-972305
• Length: 417
• Species: Xenopus tropicalis
• Alignment Length: 527
• Identity: 112/527 - (21%)
• Similarity: 168/527 - (31%)
• Gaps: 194/527 - (36%)

  Fly  1680 SESLKIDQNGQNEQNQVEDTTA---VNENNNPVAPPSPKPPMYNE------SDFDTAFSDTDE-- 1733
            :|..::|...||..:|:|....   :|...|       ||....|      .|:..|..|.||
 Frog    23 TEMREMDLQVQNAMDQLEQRVGEFFMNAKKN-------KPEWREEQMASIKKDYFKALEDADEKV 80

  Fly  1734 -------EFYDSHPQKLANELLTQKREALMAEHA---------------PMRPSNNYDIVENS-- 1774
                   :..|.|.:||..||...|.| |.|::|               |.:|.||:.:..:|
 Frog    81 QLANQIYDLVDRHLRKLDQELAKFKME-LEADNAGITEILERRSLELDTPSQPVNNHHVHSHSLG 144

  Fly  1775 --RPSTPSLPEEASAFADKREKVRNKKKKRER-KSTCKSGKLQPVASTTPPPMDRIPGMPGMIAP 1836
              |...||.....:      :.|..||.|.|. .||.          |:....:...|....::
 Frog   145 EKRKHNPSSHHSTT------DHVSEKKFKSEALLSTL----------TSDASKENTAGCRNNLS- 192

  Fly  1837 LEPPTPILSHPESSLFPVT---PLTHRQLQSSMTRMSEG------SSCSDADGQLKRSKRQRRPN 1892
                    |...::::.|.   |||...:.|..|....|      :....|..|:|..:|.....
 Frog   193 --------SSSTNNVYNVNASQPLTSYNISSLSTGAGAGAITMAAAQAVQATAQMKEGRRTSSLK 249

  Fly  1893 KFY-GYTSDDENMSAVLAPPLQVGMQLIKPQPPPQLTWAKEDLPTPPKQRNRNNNNSSHHHHSHS 1956
            ..| .:.::|          .|:|:.|.:    ...|::...|.:...|    ...||....|.|
 Frog   250 ASYEAFKNND----------FQLGISLSR----DSATYSSSALASTLTQ----TLTSSATTDSRS 296

  Fly  1957 NGGMAGSSRKRSKQRSLFGAGGSRPAKRHKPDPNDHLPPIPTLKIRPSLLPTTAPPSDSSESSSD 2021
             |..:.|:.|.:.|:|...:..|                        ||       |..|.||:.
 Frog   297 -GRKSKSNNKSASQQSSSSSSSS------------------------SL-------SSCSSSSAL 329

  Fly  2022 DEEAEVNVTSVVPTPQPAPPPVLPTPLPVALPVPPPPPPAATAFNQPIPPALLPNPGFATLQYFK 2086
            ..|.....|:.:|....                           |..:.....||
 Frog   330 AHELSHQQTAAIPESDT---------------------------NSQVDWTYDPN---------- 357

  Fly  2087 ANNIRYPIRPPAGARLAREGESVYCYCRCPYDEVS--EMIACDGDNCLIEWFHFECVGIMVAPQG 2149
                                |..||.|    ::||  ||:.||..:|.|||||:.|||:..||:|
 Frog   358 --------------------EPRYCIC----NQVSYGEMVGCDNQDCPIEWFHYGCVGLSEAPKG 398

  Fly  2150 KWFCAEC 2156
            ||:|.:|
 Frog   399 KWYCPQC 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275370
		C2H2 Zn finger	1323..1341	CDD:275370
		PHD_ING	2110..2156	CDD:276980	24/47 (51%)
ing3	NP_001008672.1	ING	3..102	CDD:404028	21/85 (25%)
		TNG2	4..409	CDD:227367	112/527 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..165		9/44 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..198		2/29 (7%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..320		11/64 (17%)
		PHD_ING3	361..405	CDD:277060	24/47 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010