DRSC/TRiP Functional Genomics Resources

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Protein Alignment MESR4 and CG11247

DIOPT Version :9

Sequence 1:NP_001097359.1 Gene:MESR4 / 36986 FlyBaseID:FBgn0034240 Length:2171 Species:Drosophila melanogaster
Sequence 2:NP_001097659.1 Gene:CG11247 / 40414 FlyBaseID:FBgn0037120 Length:522 Species:Drosophila melanogaster


Alignment Length:600 Identity:113/600 - (18%)
Similarity:215/600 - (35%) Gaps:158/600 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   935 PPALITEFQGQPDAVRRN-----SLGSDCMDMDDSLNAPEMEGSRDFTEAQKETLEPAPPSQDTQ 994
            |||......|...|::|.     ||...|:|.::.....:.....|:.:         |..:.:.
  Fly    27 PPAARESSPGPTLAIKRRKSSLASLRDACVDEEEDDGGEQDSKDDDYVQ---------PQLKKSA 82

  Fly   995 TADEPLAIQPLPPADGIMVAGPDTHTVDLQLDRPLDRFSMVDFVRLCLKSVYS-----LCLYCNH 1054
            ...||:..:               |.|..|..:...  ...|..|..|  ::|     .|..|..
  Fly    83 RKGEPVKRK---------------HHVCSQCSKEFG--GKTDLQRHML--IHSDERPHKCKDCGK 128

  Fly  1055 ARRIAVNVKQLVIHLIGQHRFTATVDSITAEELYAETIVAKL-KSF-LPNLENEYMNAASCCSLE 1117
            :.|.|||:|.   |:            .||.|...:.:.::. ||| |......:|.      |.
  Fly   129 SYRQAVNLKN---HI------------TTAHEHRKQFVCSQCPKSFALKERLRLHMR------LH 172

  Fly  1118 NGKYVEPFNERIYECFTCRFVTSTHKELYTHNRRLHIKSNI---TCVMCQTNFYSYSEILCHICP 1179
            :|       |:.|.|..|....:...:|..| ...|.|::|   .|..|..:|.:.:.:..|:..
  Fly   173 SG-------EKPYPCDLCDKKFARGGQLQQH-MVSHHKTSIQQFNCTKCSASFSTNANLRVHMER 229

  Fly  1180 GEVAGSVYDLQFRCCLCDMAPLPSAFRLMVHLRKQHQ-----ACDICLEDCQSQSKLSSHVWKHK 1239
            .|     ..::.||.:|: ....:...|..|:.::|.     .|:||.:..:....|::|:.:|.
  Fly   230 HE-----QGMEHRCSICE-NQFANELALRAHINQEHHKLTQFECEICHKMIEPDEDLATHMQRHT 288

  Fly  1240 LL--HLCYRCGIAYRNKQDISKHLFWKHGTESAGCKQCLQKRWRHVYHFCVPPAEFPCEQCGFVF 1302
            .:  |:|..|...:..|...:.|:....|.....|:.|.|                       .|
  Fly   289 AVKTHVCEVCNTYFTQKSQYNVHMRMHTGERPYQCRICHQ-----------------------TF 330

  Fly  1303 SKAIYLEVHQRMHTGDFRYACTEEGCEEKFVSRKLLLKHASSHVAKELPQAVSVEQTADAAPTEK 1367
            :.:..|::|.|.|||:..:.|  :.||::....:  |.|..:|:.|       :.:.......|.
  Fly   331 AHSSVLKLHIRKHTGEKPFRC--QLCEDEVAFSQ--LAHLKNHMKK-------IHKQQKPYMCEG 384

  Fly  1368 LED---IKEELE-----------EGEDEKEGAHNQEKLLSESLTNNETPKKEESDRIDNSIEPPL 1418
            ..|   ||.||:           :| |:..|..:::..:...|..|              :...|
  Fly   385 CHDFFKIKVELQSHVEHCAKCPVDG-DKPSGNQSEDAQILSVLRFN--------------MAVVL 434

  Fly  1419 SKSENRKRRKKSKRNKESLEDLNLIAPNLSESDSSDDSDSDAPRSSHQEQPKLPMRSSVDDLDMP 1483
            .|..:.::.::....|..::::.:.:..|::..|.||:..         .|...:|.:|::. :.
  Fly   435 KKISSAQKLRQLGYEKRLIDNVIIASLKLAQRQSHDDATM---------TPLARLRLNVEEF-LK 489

  Fly  1484 KVMLSPSSESDADEL 1498
            .::.:|:.:..:|||
  Fly   490 WIVPAPTMQKFSDEL 504

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MESR4NP_001097359.1 C2H2 Zn finger 1272..1288 CDD:275368 3/15 (20%)
C2H2 Zn finger 1295..1315 CDD:275370 4/19 (21%)
C2H2 Zn finger 1323..1341 CDD:275370 4/17 (24%)
PHD_ING 2110..2156 CDD:276980
CG11247NP_001097659.1 COG5048 <88..247 CDD:227381 42/212 (20%)
C2H2 Zn finger 95..115 CDD:275368 4/23 (17%)
zf-H2C2_2 107..132 CDD:290200 6/26 (23%)
C2H2 Zn finger 123..144 CDD:275368 9/35 (26%)
C2H2 Zn finger 152..172 CDD:275368 5/25 (20%)
zf-H2C2_2 165..189 CDD:290200 7/36 (19%)
C2H2 Zn finger 180..200 CDD:275368 4/20 (20%)
COG5048 <192..369 CDD:227381 43/210 (20%)
C2H2 Zn finger 210..230 CDD:275370 4/19 (21%)
C2H2 Zn finger 238..260 CDD:275371 4/22 (18%)
C2H2 Zn finger 267..287 CDD:275368 5/19 (26%)
C2H2 Zn finger 295..315 CDD:275368 4/19 (21%)
zf-H2C2_2 309..332 CDD:290200 6/45 (13%)
C2H2 Zn finger 323..343 CDD:275368 7/42 (17%)
C2H2 Zn finger 351..374 CDD:275368 7/33 (21%)
C2H2 Zn finger 382..399 CDD:275368 6/16 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24393
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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