Protein Alignment MESR4 and ing3

DIOPT Version :9

• Sequence 1: NP_001097359.1
• Gene: MESR4 / 36986
• FlyBaseID: FBgn0034240
• Length: 2171
• Species: Drosophila melanogaster
• Sequence 2: NP_957231.1
• Gene: ing3 / 393911
• ZFINID: ZDB-GENE-040109-3
• Length: 416
• Species: Danio rerio
• Alignment Length: 549
• Identity: 117/549 - (21%)
• Similarity: 166/549 - (30%)
• Gaps: 239/549 - (43%)

  Fly  1680 SESLKIDQNGQNEQNQVEDTTAVNE-----NNNPVAPPSPKPPMYNE------SDFDTAFSDTDE 1733
            :|..::|...||..:|:|.  .|||     ..|       ||....|      .|:..|..|.||
Zfish    23 TEMREMDLQVQNAMDQLEQ--RVNEFFTNAKKN-------KPEWREEQMEIIKKDYYKALEDADE 78

  Fly  1734 ---------EFYDSHPQKLANELLTQKREALMAEHA---------------PMRPSNNYDI---- 1770
                     :..|.|.:||..||...|.| |.|::|               |.:|.||:.:
Zfish    79 KVQLANQIYDLVDRHLRKLDQELAKFKME-LEADNAGITEILERRSLEMDSPSQPVNNHHVHSHT 142

  Fly  1771 -VENSRPSTPSLPEEASAFADKREKVRNKKKKRE-------------------RKSTCKSGKLQP 1815
             ||..:.|||:        ....|.|..||.|.|                   ..||..|..:..
Zfish   143 TVEKRKYSTPA--------HHTTEHVPEKKFKSEALLSTLTSDATKENTPGCRANSTSSSNSMYN 199

  Fly  1816 VAS----TTPPPMDRIPGMP----GMIAPLEPPTPILSHPESSLFPVTPLTHRQLQSSMTRMSEG 1872
            |.|    |:...:..:|..|    |.|:                     :...|...:..:|.||
Zfish   200 VNSSQSLTSSYNLSPLPAGPAAGAGAIS---------------------MAAAQAVQATAQMKEG 243

  Fly  1873 SSCSDADGQLKRSKRQRRPNKFYG--YTSDDEN---MSAVLAPPLQVGMQLIKPQPPPQLTWAKE 1932
            ...|    .||.|....:.|.|.|  :|...::   .|:.||..|          ..|..:....
Zfish   244 RRTS----SLKASYEAVKNNDFLGRDFTMSRDSSSYSSSALASTL----------TQPLTSTNSS 294

  Fly  1933 DLPTPPKQRNRNNNNSSHHHHSHSNGGMAGSSRKRSKQRSLFGAGGSRPAKRHKPDPNDHLPPIP 1997
            |..|  .::.::|..||:|..|.|:...:.||...|.            |..|:
Zfish   295 DSRT--ARKTKSNTKSSNHQSSSSSSSSSLSSCSSSS------------ALAHE----------- 334

  Fly  1998 TLKIRPSLLPTTAPPSDSSESSSDDEEAEVNVTSVVPTPQPAPPPVLPTPLPVALPVPPPPPPAA 2062
                   |:.||...:|:|             :.|..|..|
Zfish   335 -------LVQTTVTETDTS-------------SQVDWTYDP------------------------ 355

  Fly  2063 TAFNQPIPPALLPNPGFATLQYFKANNIRYPIRPPAGARLAREGESVYCYCRCPYDEVSEMIACD 2127
               |:|                                          .||.|......||:.||
Zfish   356 ---NEP------------------------------------------RYCICNQVSYGEMVGCD 375

  Fly  2128 GDNCLIEWFHFECVGIMVAPQGKWFCAEC 2156
            ..:|.|||||:.|||:..||:|||:|.:|
Zfish   376 NQDCPIEWFHYGCVGLTEAPKGKWYCPQC 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275370
		C2H2 Zn finger	1323..1341	CDD:275370
		PHD_ING	2110..2156	CDD:276980	22/45 (49%)
ing3	NP_957231.1	ING	3..102	CDD:289749	23/87 (26%)
		TNG2	4..408	CDD:227367	117/549 (21%)
		PHD_ING3	360..404	CDD:277060	22/43 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910