DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MESR4 and Ing3

DIOPT Version :9

Sequence 1:	NP_001097359.1	Gene:	MESR4 / 36986	FlyBaseID:	FBgn0034240	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	NP_573316.1	Gene:	Ing3 / 32853	FlyBaseID:	FBgn0030945	Length:	686	Species:	Drosophila melanogaster

Alignment Length:	254	Identity:	64/254 - (25%)
Similarity:	84/254 - (33%)	Gaps:	69/254 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1944 NNNNSSHHHHSHSNGGMAGSSRKRSK-------QRSLFGAGGSRPAKRHKPDPNDHLPPIPTLKI 2001
            ::..|.|.|||.|:.|..|.......       ..|..|.||...:...:......|....|
  Fly   449 SSTGSHHSHHSQSHHGGHGHGHGHGHGHGHGHGHHSSSGHGGGHSSHHQEKKQKKKLTTALT--- 510

  Fly  2002 RPSLLPTTAPPSDSSESSSDDEEAEVNVTSVVPTPQPAPPPVLPTPLPVALPVPPPPPPAATAFN 2066
                |||..|.:.||..:|....:.:::.||         ..|.|...:|      ...|.|.:.
  Fly   511 ----LPTVQPTAGSSSGNSIGSSSSISLESV---------NKLTTSAALA------AASATTTYM 556

  Fly  2067 QPIPPALLP----NPGFATLQYFKANNIRYPIRPPAG-------------------------ARL 2102
            .....|||.    ..|...|....|..:      |||                         ...
  Fly   557 SVGGQALLAMTPGGGGGGNLAESSAEGV------PAGMIAMNLPTTTVTPGSSLTIGENGLVVEQ 615

  Fly  2103 AREGESVY-----CYCRCPYDEVSEMIACDGDNCLIEWFHFECVGIMVAPQGKWFCAEC 2156
            ..|||..|     .||.|......:|:|||.|.|..||||:.||||...|:|||:|.:|
  Fly   616 TNEGEWSYDPNEPRYCTCNQVSYGDMVACDNDACPYEWFHYPCVGITQPPKGKWYCPKC 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275370
		C2H2 Zn finger	1323..1341	CDD:275370
		PHD_ING	2110..2156	CDD:276980	23/50 (46%)
Ing3	NP_573316.1	ING	3..103	CDD:289749
Ing3	NP_573316.1	PHD_ING3	630..674	CDD:277060	22/43 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910