DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MESR4 and Ing4

DIOPT Version :9

Sequence 1:	NP_001097359.1	Gene:	MESR4 / 36986	FlyBaseID:	FBgn0034240	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	XP_006237411.1	Gene:	Ing4 / 297597	RGDID:	1309407	Length:	249	Species:	Rattus norvegicus

Alignment Length:	211	Identity:	53/211 - (25%)
Similarity:	67/211 - (31%)	Gaps:	88/211 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly  1948 SSHHHHSHSNGGMAGSSRKRSKQRSLFGAGGSRPAKRHKPDPNDHLPPIPTLKIRPSLLPTTAPP 2012
            ||.:..|.|.|...|.::|..|            |.|.:
  Rat   118 SSDYDSSSSKGKRKGRTQKEKK------------AARAR-------------------------- 144

  Fly  2013 SDSSESSSDDEEAEVNVTSVVPTPQPAPPPVLPTPLPVALPVPPPPPPAATAFNQPIPPALLPNP 2077
               |:..:.||||               |......|.:....|....|:.| |....|..:|.
  Rat   145 ---SKGKNSDEEA---------------PKAAQKKLKLVRTSPEYGMPSVT-FGSVHPSDVLD-- 188

  Fly  2078 GFATLQYFKANNIRYPIRPPAGARLAREGESVYCYCRCPYDEVS--EMIACDGDNCLIEWFHFEC 2140
                          .|:.|         .|..||.|.    :||  |||.||..:|.||||||.|
  Rat   189 --------------MPVDP---------NEPTYCLCH----QVSYGEMIGCDNPDCSIEWFHFAC 226

  Fly  2141 VGIMVAPQGKWFCAEC 2156
            ||:...|:|||||..|
  Rat   227 VGLTTKPRGKWFCPRC 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275370
		C2H2 Zn finger	1323..1341	CDD:275370
		PHD_ING	2110..2156	CDD:276980	26/47 (55%)
Ing4	XP_006237411.1	TNG2	7..245	CDD:227367	53/211 (25%)
Ing4	XP_006237411.1	ING_ING4	11..104	CDD:341095
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910