DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MESR4 and sfc2

DIOPT Version :9

Sequence 1:	NP_001097359.1	Gene:	MESR4 / 36986	FlyBaseID:	FBgn0034240	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	NP_594670.1	Gene:	sfc2 / 2542887	PomBaseID:	SPAC144.09c	Length:	374	Species:	Schizosaccharomyces pombe

Alignment Length:	371	Identity:	91/371 - (24%)
Similarity:	129/371 - (34%)	Gaps:	114/371 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1102 NLENEYMNAASC-----CSLE--NGKYVEP----------FNERIYECFTCRFVTSTHKELYTHN 1149
            ::|.|..|..|.     |..|  ..||..|          .|||   .|.|.: |...|..|
pombe     8 SIEIESKNLRSAKKIFHCPYEECGKKYSRPSLLEQHLRTHSNER---PFVCDY-TGCSKAFY--- 65

  Fly  1150 RRLHIKSNITCVMCQTNFYSYSEILCHICPGEVAGSVYDLQFRCCLCDMAPLPSAFRLMVHLRKQ 1214
            |:.|:|.:   ..|.||...:|   ||          ||      .||     :.|....||.:.
pombe    66 RKSHLKIH---KRCHTNVKPFS---CH----------YD------GCD-----AQFYTQQHLERH 103

  Fly  1215 ---H----------QACDICLEDCQSQSKLSSHV---WKHKLLHLC-YR-CGIAYRNKQDISKHL 1261
               |          :.||.|....|   :|.||:   ..|.|.:.| |: |.:.:..||.:..|:
pombe   104 IEVHRKPKPYACTWEGCDECFSKHQ---QLRSHISACHTHLLPYPCTYQDCELRFATKQKLQNHV 165

  Fly  1262 FWKHG---TESAGCKQCLQ----KRW----RHVYHFCVPPAEFPCEQCGFVFSKAIYLEVHQRMH 1315
            ...|.   :.|...:.|:.    ::|    .|:....||    .|..||..|..|.:|..|..:|
pombe   166 NRAHEKIISYSCPHESCVGHEGFEKWSQLQNHIREAHVP----SCSICGRQFKTAAHLRHHVVLH 226

  Fly  1316 TGDFR----YACTEEGCEEKFVSRKLLLKHASSHVAKELPQAVSVEQTADAAPTEKLEDIKEELE 1376
            .....    |.|..|||::.|.....|.||.|  |..|...|...:........:.:  ::..||
pombe   227 QTTLEERKTYHCPMEGCKKSFTRSSALKKHIS--VIHEGNMAFHCDSCGTKFGYKHM--LQRHLE 287

  Fly  1377 EGEDEK----------------EGA--HNQ-EKLLSESLTNNETPK 1403
            .|..:|                ||.  |:| ||.||.:|.::...|
pombe   288 RGTCKKAHKPYINECGIKHDGIEGVAIHDQKEKELSSNLVSDVAKK 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368	3/23 (13%)
		C2H2 Zn finger	1295..1315	CDD:275370	7/19 (37%)
		C2H2 Zn finger	1323..1341	CDD:275370	6/17 (35%)
		PHD_ING	2110..2156	CDD:276980
sfc2	NP_594670.1	COG5048	1..374	CDD:227381	91/371 (25%)
		C2H2 Zn finger	28..47	CDD:275368	4/18 (22%)
		C2H2 Zn finger	55..77	CDD:275368	7/28 (25%)
		C2H2 Zn finger	85..107	CDD:275368	9/42 (21%)
		C2H2 Zn finger	115..138	CDD:275368	7/25 (28%)
		C2H2 Zn finger	146..165	CDD:275368	5/18 (28%)
		C2H2 Zn finger	206..226	CDD:275368	7/19 (37%)
		C2H2 Zn finger	238..261	CDD:275368	10/24 (42%)
		C2H2 Zn finger	269..286	CDD:275368	0/18 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100