DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MESR4 and athp-3

DIOPT Version :9

Sequence 1:	NP_001097359.1	Gene:	MESR4 / 36986	FlyBaseID:	FBgn0034240	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	NP_503022.1	Gene:	athp-3 / 178479	WormBaseID:	WBGene00013799	Length:	286	Species:	Caenorhabditis elegans

Alignment Length:	246	Identity:	47/246 - (19%)
Similarity:	81/246 - (32%)	Gaps:	81/246 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1460 APRSSHQEQPKLPMRSSVDDLDMPKVMLSPSSESDADELDGKSKLEDKEEKPLDGSTEEKALDAD 1524
            |..|..::|.|:|::             :|:.|:....  |:.:.:..|||........|
Worm    74 AQMSKQRKQKKVPVK-------------NPAGEAKRGR--GRPRKQSSEEKVQIPKVVVK----- 118

  Fly  1525 DELEPKKEEDQVDVSIWKNLLQNQAVAIP-EEQAVKDEEREDSLVNLPPAKLHVAWSDHDYCKLY 1588
              .||||.......:.|     :|.||:. ::|..:...|        |.|:
Worm   119 --FEPKKRGRPAGAAKW-----SQEVAVVLQKQPQRKRGR--------PLKI------------- 155

  Fly  1589 RTPAPSPV-KQKSANKSSIKTPGENASSDSDSSSSSSSSDSDSSSCSCGSNCSCSSSNSSSSSGN 1652
             .....|| .||..:|       :|:...:.....:...:..:....||            ::..
Worm   156 -AKKIEPVFHQKKESK-------QNSEEKALIQQEAVKGEPKNRGRPCG------------AAER 200

  Fly  1653 SDDSDSSTARGSPQKRSRKKSLKVKKSSESLKIDQNGQNEQNQVEDTTAVN 1703
            |.:......:..|:||.|           .|||.:|.:.|.||.:||..|:
Worm   201 SREVVKKLQKQPPRKRGR-----------PLKIAKNMEPEINQKKDTKQVH 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275370
		C2H2 Zn finger	1323..1341	CDD:275370
		PHD_ING	2110..2156	CDD:276980
athp-3	NP_503022.1	Asp-B-Hydro_N	<81..241	CDD:191249	45/239 (19%)
athp-3	NP_503022.1	PHD_TCF19_like	241..284	CDD:276992	47/246 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900