DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MESR4 and Y43H11AL.1

DIOPT Version :9

Sequence 1:	NP_001097359.1	Gene:	MESR4 / 36986	FlyBaseID:	FBgn0034240	Length:	2171	Species:	Drosophila melanogaster
Sequence 2:	NP_001254007.1	Gene:	Y43H11AL.1 / 173408	WormBaseID:	WBGene00021545	Length:	490	Species:	Caenorhabditis elegans

Alignment Length:	481	Identity:	91/481 - (18%)
Similarity:	148/481 - (30%)	Gaps:	168/481 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1728 FSDTDEEFYDSHPQKLANELLTQKREALMAEHAPMRPSNNYDIVENSRPSTPSLPEEASAFADKR 1792
            :...|:.:...:...:.|...|........|::.|        .::.|.||.|     .....||
Worm   126 YQTLDKNYRGEYQSSIPNVRTTNSGRQRTREYSVM--------TDDDRASTSS-----GTLFTKR 177

  Fly  1793 EKVRNKKKKRERKSTCKSGKLQPVASTTPPPMDRIPGMPGMIAPLEPPTPILSHPESSLFPVTPL 1857
            |           ||:.|.|..:|..:......||.              |:.|:..|:
Worm   178 E-----------KSSLKKGPGRPRNAFKMAHFDRF--------------PVDSNASSA------- 210

  Fly  1858 THRQLQSSMTRMSEGSSCSDADGQLKRSKRQRRPN-----------KF---------------YG 1896
                 :|||    |.|.|..:....|.||..::.|           ||               ..
Worm   211 -----RSSM----EPSECGGSQNTKKLSKYMKKKNEKMRKEEQKLSKFDVKREVDTGDYESFALN 266

  Fly  1897 YTSDDENMSAVLAPPLQVGMQLIK--PQPPPQLTWAKEDLPTPPK-------------------Q 1940
            ..::|::| .:.:..:..|..|::  .:...:|......||:||:                   .
Worm   267 QWNNDDDM-GMTSSKMMNGSSLMELCEEEEAELLDCFAGLPSPPRGMMDVLDVTESDVCGMDLYP 330

  Fly  1941 RNRNNNNSSHHHHSHSNGGMAGSSRKRSKQRSLFGAGGSRPAKRHKPDPNDHLPPIPTLKIRPSL 2005
            ::..:.|.....|.   |..|.||:..:.:|:...|..                        |..
Worm   331 KDHKSENYDDFRHP---GASAMSSQSFTHKRANNAARA------------------------PPA 368

  Fly  2006 LPTTAPPSDSSESSSDDEEAEVNVTSVVPTPQPAPPPVLPTPLPVALPVPPPPPPAATAFNQPIP 2070
            :.|.|..|..|:|:....|.:.:.|                           ||...|.|.....
Worm   369 VATAAAVSSFSDSTIIRYEKQRSHT---------------------------PPQRNTLFGSISD 406

  Fly  2071 PALLPNPGFAT---LQYFKANNIRYPIRPPAGARLAREGESVYCYCRCPYDEVSEMIACDGDNCL 2132
            .:....|...|   .:...:|..|        .:..||.|. :|.|.........|:.|:..||.
Worm   407 TSFSGRPRKLTDRVTEMIISNRER--------TKKYREQEE-WCICNGMNINSGMMVECENKNCP 462

  Fly  2133 IEWFHFECVGIMVAPQGKWFCAECRP 2158
            |:||||||||::.||..:|:|.:|.|
Worm   463 IKWFHFECVGLLAAPLDEWYCTDCNP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368
		C2H2 Zn finger	1295..1315	CDD:275370
		C2H2 Zn finger	1323..1341	CDD:275370
		PHD_ING	2110..2156	CDD:276980	19/45 (42%)
Y43H11AL.1	NP_001254007.1	PHD_ING	440..486	CDD:276980	19/45 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010