DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpL18A and RPL18A

DIOPT Version :9

Sequence 1:	NP_523774.1	Gene:	RpL18A / 36985	FlyBaseID:	FBgn0010409	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_000971.1	Gene:	RPL18A / 6142	HGNCID:	10311	Length:	176	Species:	Homo sapiens

Alignment Length:	176	Identity:	121/176 - (68%)
Similarity:	146/176 - (82%)	Gaps:	0/176 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRAKGLLKEYEVVGRKLPSEKEPQTPLYKMRIFAPDNIVAKSRFWYFLRQLKKFKKTTGEIVSIK 65
            |:|.|.|:||:||||.||:.|....|||:||||||:::|||||||||:.||||.||::||||...
Human     1 MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCG 65

  Fly    66 QVYETSPVKIKNFGIWLRYDSRSGTHNMYREYRDLTVGGAVTQCYRDMGARHRARAHSIQIIKVD 130
            ||:|.||:::||||||||||||||||||||||||||..|||||||||||||||||||||||:||:
Human    66 QVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVE 130

  Fly   131 SIPAAKTRRVHVKQFHDSKIKFPLVQRVHHKGNRKLFSFRKPRTYF 176
            .|.|:|.||..|||||||||||||..||..:.::..|:.::|.|:|
Human   131 EIAASKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpL18A	NP_523774.1	RPL20A	69..153	CDD:225068	69/83 (83%)
RPL18A	NP_000971.1	RPL20A	69..153	CDD:225068	69/83 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158670
Domainoid	1	1.000	200	1.000	Domainoid score	I3053
eggNOG	1	0.900	-	-		E1_COG2157
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68104
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3203
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53815
OrthoDB	1	1.010	-	-		D1265349at2759
OrthoFinder	1	1.000	-	-		FOG0002143
OrthoInspector	1	1.000	-	-		oto90399
orthoMCL	1	0.900	-	-		OOG6_101208
Panther	1	1.100	-	-	LDO	PTHR10052
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1116
SonicParanoid	1	1.000	-	-		X1428
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800