DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyp33 and CPR2

DIOPT Version :9

Sequence 1:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_011924.1	Gene:	CPR2 / 856454	SGDID:	S000001099	Length:	205	Species:	Saccharomyces cerevisiae

Alignment Length:	175	Identity:	89/175 - (50%)
Similarity:	108/175 - (61%)	Gaps:	3/175 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 GPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQG-YGYKGCSFHR 190
            |..:.:..|....:|||||..|....||||:.|...|.||||:||.:|.|.... .|:.|.:|||
Yeast    24 GELIDQDDEVITQKVFFDIEHGEEKVGRIVIGLYGKVCPKTAKNFYKLSTTTNSKKGFIGSTFHR 88

  Fly   191 VIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICTT-KT 254
            |||.||.||||||:..|.|||||||..|.||||.|||:..|.|||||.|.:||||||||.|| :.
Yeast    89 VIPNFMVQGGDFTDGTGVGGKSIYGDTFPDENFTLKHDRKGRLSMANRGKDTNGSQFFITTTEEA 153

  Fly   255 DWLDNKHVVFGHVISGAEVVRKMERCG-SKSGTPSQKIVIYSCGE 298
            .|||.||||||.|:.|.:||..::... ..:..|.:.:.|..|||
Yeast   154 SWLDGKHVVFGQVVDGMDVVNYIQHVSRDANDKPLEAVKIAKCGE 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	84/160 (53%)
CPR2	NP_011924.1	cyclophilin	37..197	CDD:412213	84/159 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810