DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyp33 and CPR7

DIOPT Version :9

Sequence 1:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_012566.1	Gene:	CPR7 / 853489	SGDID:	S000003793	Length:	393	Species:	Saccharomyces cerevisiae

Alignment Length:	193	Identity:	76/193 - (39%)
Similarity:	96/193 - (49%)	Gaps:	32/193 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 RNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCT--------HEQGYGYKGCSFHRVIP 193
            ::|.|:.||.|.....||||..|..:..|||.|||.:||.        .:|...|||..||||:.
Yeast     3 QDPLVYLDISIDKKPIGRIVCKLFREKAPKTTENFYKLCAGDVKSPLKDQQYLSYKGNGFHRVVK 67

  Fly   194 EFMCQGGDF---------TNNNGTGGKSIYGK----KFNDENF---NLKHNSFG------TLSMA 236
            .||.|.||.         :::.|.||.|||..    |.:||:|   |.:..:.|      ||.||
Yeast    68 NFMIQAGDIVFGTQKDSSSSSVGKGGCSIYADKEEVKTDDESFCYGNFEDENLGEFVEPFTLGMA 132

  Fly   237 NSGA-NTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKS-GTPSQKIVIYSCG 297
            |.|: |||.|||||.|.....|:.||.:||.|:.|..|||.:|.|...| |.|...:.|..||
Yeast   133 NLGSPNTNNSQFFITTYAAPHLNGKHSIFGQVVHGKSVVRTIENCRVDSDGVPESDVRISDCG 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	74/189 (39%)
CPR7	NP_012566.1	cyclophilin	5..195	CDD:412213	74/189 (39%)
		TPR	<233..383	CDD:223533
		TPR repeat	274..321	CDD:276809
		TPR_16	296..353	CDD:404335
		TPR_1	330..363	CDD:395414
		TPR repeat	330..353	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810