DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyp33 and CPR4

DIOPT Version :9

Sequence 1:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_009995.1	Gene:	CPR4 / 850433	SGDID:	S000000665	Length:	318	Species:	Saccharomyces cerevisiae

Alignment Length:	205	Identity:	65/205 - (31%)
Similarity:	85/205 - (41%)	Gaps:	42/205 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 VRVKEDSFKPIWADDDWLQKHAGATLQPEGEPEAEKVETPST--GPAVIEKAEKRNPQVFFDIRI 147
            |.....|.|.|.:.|        ..||.:.||     ..|:|  |...||         :||...
Yeast    18 VHAAPSSGKQITSKD--------VDLQKKYEP-----SPPATHRGIITIE---------YFDPVS 60

  Fly   148 GGNDAGRIVMLLRADVVPKTAENFRQLCTHEQG------------YGYKGCSFHRVIPEFMCQGG 200
            .......:...|...|||||..||..|....:.            |.|:....::|.|....|||
Yeast    61 KSMKEADLTFELYGTVVPKTVNNFAMLAHGVKAVIEGKDPNDIHTYSYRKTKINKVYPNKYIQGG 125

  Fly   201 DFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICTTKTDW---LDNKHV 262
            ....:  .|..::||.||:||||.|||:....|:||..|.::|.|:|.| |||.|.   ||.|.|
Yeast   126 VVAPD--VGPFTVYGPKFDDENFYLKHDRPERLAMAYFGPDSNTSEFII-TTKADGNEELDGKSV 187

  Fly   263 VFGHVISGAE 272
            |||.:.||.:
Yeast   188 VFGQITSGLD 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	51/149 (34%)
CPR4	NP_009995.1	cyclophilin	67..219	CDD:238194	49/134 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900