DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyp33 and Ppih

DIOPT Version :9

Sequence 1:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001103600.1	Gene:	Ppih / 66101	MGIID:	106499	Length:	188	Species:	Mus musculus

Alignment Length:	146	Identity:	91/146 - (62%)
Similarity:	106/146 - (72%)	Gaps:	5/146 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 NPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHE---QG--YGYKGCSFHRVIPEFMC 197
            ||.||||:.|||.:.||:.:.|.|||||||||||||.||.|   .|  .||||.:|||||.:||.
Mouse    10 NPVVFFDVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMI 74

  Fly   198 QGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICTTKTDWLDNKHV 262
            |||||.|.:|||..|||...|.||||.|:|::.|.|||||||.:|||.||||..:|.||||.|||
Mouse    75 QGGDFVNGDGTGVASIYRGPFADENFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWLDGKHV 139

  Fly   263 VFGHVISGAEVVRKME 278
            |||.:|.|..|:||:|
Mouse   140 VFGKIIDGLLVMRKIE 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	90/145 (62%)
Ppih	NP_001103600.1	cyclophilin_ABH_like	11..155	CDD:238907	89/143 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810