DRSC/TRiP Functional Genomics Resources

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Protein Alignment cyp33 and RANBP2

DIOPT Version :10

Sequence 1:NP_523773.1 Gene:cyp33 / 36984 FlyBaseID:FBgn0028382 Length:300 Species:Drosophila melanogaster
Sequence 2:XP_005264059.1 Gene:RANBP2 / 5903 HGNCID:9848 Length:3258 Species:Homo sapiens


Alignment Length:243 Identity:101/243 - (41%)
Similarity:138/243 - (56%) Gaps:38/243 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 KPVRVKEDSFKPIWADDDWLQKHAGATLQPEGEPEAEKV----ETPSTGPA-------------- 129
            ||:.|..::.  :|...|:          .:||.:.|::    :|......              
Human  3028 KPLNVSNNAL--VWTASDY----------ADGEAKVEQLAVRFKTKEVADCFKKTFEECQQNLMK 3080

  Fly   130 --------VIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQGYGYKGC 186
                    ..|.:::.||.||||:...|...|||.|.|.:::||:||||||.|||.|:|:|:|..
Human  3081 LQKGHVSLAAELSKETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKNS 3145

  Fly   187 SFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICT 251
            .||||||:|:|||||.|.::||||:||||.||.||||::||...|.|||||.|.|||.|||.|..
Human  3146 IFHRVIPDFVCQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQGQNTNNSQFVITL 3210

  Fly   252 TKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVIYSCGEL 299
            .|.:.||.||||||.|..|.:.|:|:|..||..|:..::|.|..||::
Human  3211 KKAEHLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITECGQI 3258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cyp33NP_523773.1 RRM_PPIE 8..82 CDD:409783
cyclophilin_ABH_like 139..297 CDD:238907 88/157 (56%)
RANBP2XP_005264059.1 LapB <33..222 CDD:442196
TPR repeat 59..89 CDD:276809
TPR repeat 94..123 CDD:276809
RanBD1_RanBP2-like 1186..1302 CDD:270203
zf-RanBP 1351..1381 CDD:395516
RanBP2-type Zn finger 1355..1375 CDD:275375
zf-RanBP 1415..1443 CDD:395516
RanBP2-type Zn finger 1419..1438 CDD:275375
zf-RanBP 1479..1508 CDD:395516
RanBP2-type Zn finger 1483..1502 CDD:275375
zf-RanBP 1543..1572 CDD:395516
RanBP2-type Zn finger 1547..1566 CDD:275375
zf-RanBP 1606..1635 CDD:395516
RanBP2-type Zn finger 1610..1629 CDD:275375
zf-RanBP 1665..1694 CDD:395516
RanBP2-type Zn finger 1669..1688 CDD:275375
zf-RanBP 1724..1753 CDD:395516
RanBP2-type Zn finger 1728..1747 CDD:275375
zf-RanBP 1781..1809 CDD:395516
RanBP2-type Zn finger 1785..1804 CDD:275375
RanBD2_RanBP2-like 2027..2143 CDD:269998
RanBD3_RanBP2-like 2324..2440 CDD:270204
IR1-M 2657..2719 CDD:463488
IR1-M 2735..2791 CDD:463488
RanBD4_RanBP2-like 2959..3075 CDD:269999 9/58 (16%)
cyclophilin_ABH_like 3098..3256 CDD:238907 88/157 (56%)
Blue background indicates that the domain is not in the aligned region.

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