DRSC/TRiP Functional Genomics Resources

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Protein Alignment cyp33 and PPID

DIOPT Version :9

Sequence 1:NP_523773.1 Gene:cyp33 / 36984 FlyBaseID:FBgn0028382 Length:300 Species:Drosophila melanogaster
Sequence 2:NP_005029.1 Gene:PPID / 5481 HGNCID:9257 Length:370 Species:Homo sapiens


Alignment Length:193 Identity:109/193 - (56%)
Similarity:127/193 - (65%) Gaps:21/193 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 PEAEKVETPSTGPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQG 180
            |:| |...||            ||:||||:.|||...||||:.|.||:|||||||||.|||.|:|
Human     6 PQA-KPSNPS------------NPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKG 57

  Fly   181 YG--------YKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMAN 237
            .|        :|||.|||:|.:||.|||||:|.|||||:||||:||.||||:.||:..|.|||||
Human    58 IGHTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSMAN 122

  Fly   238 SGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVIYSCGELK 300
            :|.|||||||||.|..|..||.||||||.||.|..|.|.:|....|...|::..||..|||||
Human   123 AGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAECGELK 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cyp33NP_523773.1 RRM_PPIE 8..80 CDD:240793
cyclophilin_ABH_like 139..297 CDD:238907 98/165 (59%)
PPIDNP_005029.1 cyclophilin_ABH_like 16..182 CDD:238907 98/165 (59%)
Chaperone activity. /evidence=ECO:0000250 185..215 1/1 (100%)
PLN03088 192..>362 CDD:330826
Interaction with HSP90AB1. /evidence=ECO:0000250 214..370
TPR repeat 224..267 CDD:276809
TPR repeat 272..302 CDD:276809
TPR repeat 307..333 CDD:276809
TPR repeat 341..364 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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