DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyp33 and PPIL3

DIOPT Version :9

Sequence 1:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_115861.1	Gene:	PPIL3 / 53938	HGNCID:	9262	Length:	165	Species:	Homo sapiens

Alignment Length:	134	Identity:	53/134 - (39%)
Similarity:	70/134 - (52%)	Gaps:	9/134 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 DAGRIVMLLRADVVPKTAENFRQLCTHEQGYGYKGCSFHRVIP----EFMCQGGDFTNNNGTGGK 211
            |.|.|.:.:..:..|||.| ....|..:.|..::.....:..|    :..|..   ....|.||.
Human     8 DVGDIKIEVFCERTPKTCE-MESRCVPQAGVQWRDLGSLQPPPPGFKQVFCLS---LPRTGRGGN 68

  Fly   212 SIYGKKFNDE-NFNLKHNSFGTLSMANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVR 275
            ||:||||.|| :..||||..|.:||||:|.|||||||||...|...||.|:.|||.||.|.|.:.
Human    69 SIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKVIDGLETLD 133

  Fly   276 KMER 279
            ::|:
Human   134 ELEK 137

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	53/134 (40%)
PPIL3	NP_115861.1	cyclophilin	1..158	CDD:294131	53/134 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900