Protein Alignment cyp33 and Ppid

DIOPT Version :10

• Sequence 1: NP_523773.1
• Gene: cyp33 / 36984
• FlyBaseID: FBgn0028382
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001004279.1
• Gene: Ppid / 361967
• RGDID: 1303174
• Length: 370
• Species: Rattus norvegicus
• Alignment Length: 197
• Identity: 106/197 - (53%)
• Similarity: 126/197 - (63%)
• Gaps: 25/197 - (12%)

  Fly   112 PEGEPEAEKVETPSTGPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCT 176
            |.|:|                 :..:||:||||:.|||...||||:.|.||:|||||||||.|||
  Rat     6 PAGKP-----------------SNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCT 53

  Fly   177 HEQGYG--------YKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTL 233
            .|:|.|        :|||.|||:|.:||.|||||:|.|||||:||||:||.||||:.||:..|.|
  Rat    54 GEKGTGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLL 118

  Fly   234 SMANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVIYSCGE 298
            ||||:|.|||||||||.|..|..||.||||||.||.|..|.|.:|........|::..||..|||
  Rat   119 SMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARMLENVEVNGEKPAKLCVIAECGE 183

  Fly   299 LK 300
            ||
  Rat   184 LK 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..82	CDD:409783
		cyclophilin_ABH_like	139..297	CDD:238907	97/165 (59%)
Ppid	NP_001004279.1	cyclophilin_ABH_like	16..182	CDD:238907	97/165 (59%)
		Chaperone activity. /evidence=ECO:0000250	185..215		1/1 (100%)
		TPR	213..>367	CDD:440225
		Interaction with HSP90AB1. /evidence=ECO:0000250	214..370
		TPR repeat	223..251	CDD:276809
		TPR repeat	272..302	CDD:276809
		TPR repeat	307..335	CDD:276809
		TPR repeat	341..364	CDD:276809