DRSC/TRiP Functional Genomics Resources

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Protein Alignment cyp33 and Ppid

DIOPT Version :9

Sequence 1:NP_523773.1 Gene:cyp33 / 36984 FlyBaseID:FBgn0028382 Length:300 Species:Drosophila melanogaster
Sequence 2:NP_001004279.1 Gene:Ppid / 361967 RGDID:1303174 Length:370 Species:Rattus norvegicus


Alignment Length:197 Identity:106/197 - (53%)
Similarity:126/197 - (63%) Gaps:25/197 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   112 PEGEPEAEKVETPSTGPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCT 176
            |.|:|                 :..:||:||||:.|||...||||:.|.||:|||||||||.|||
  Rat     6 PAGKP-----------------SNSKNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCT 53

  Fly   177 HEQGYG--------YKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTL 233
            .|:|.|        :|||.|||:|.:||.|||||:|.|||||:||||:||.||||:.||:..|.|
  Rat    54 GEKGTGPTTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLL 118

  Fly   234 SMANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVIYSCGE 298
            ||||:|.|||||||||.|..|..||.||||||.||.|..|.|.:|........|::..||..|||
  Rat   119 SMANAGPNTNGSQFFITTVPTPHLDGKHVVFGQVIKGLGVARMLENVEVNGEKPAKLCVIAECGE 183

  Fly   299 LK 300
            ||
  Rat   184 LK 185

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cyp33NP_523773.1 RRM_PPIE 8..80 CDD:240793
cyclophilin_ABH_like 139..297 CDD:238907 97/165 (59%)
PpidNP_001004279.1 cyclophilin_ABH_like 16..182 CDD:238907 97/165 (59%)
Chaperone activity. /evidence=ECO:0000250 185..215 1/1 (100%)
3a0801s09 192..>330 CDD:273380
Interaction with HSP90AB1. /evidence=ECO:0000250 214..370
TPR repeat 223..251 CDD:276809
TPR repeat 272..302 CDD:276809
TPR repeat 307..335 CDD:276809
TPR repeat 341..364 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0652
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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