Protein Alignment cyp33 and PPIL6

DIOPT Version :10

• Sequence 1: NP_523773.1
• Gene: cyp33 / 36984
• FlyBaseID: FBgn0028382
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001104768.2
• Gene: PPIL6 / 285755
• HGNCID: 21557
• Length: 337
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 89/332 - (26%)
• Similarity: 141/332 - (42%)
• Gaps: 91/332 - (27%)

  Fly    13 LADEVTERLLNNAFIPFGDIADIQMPADYESQRHRGFAFIEYEQSE---------DAAAAIDNMN 68
            :|....|.|.||....|.|  .|.:|.       :.||:.:|.|.:         :.::::.:..
Human    39 IAKSAAENLKNNHPSKFED--PILVPL-------QEFAWHQYLQEKKRELKNETWEYSSSVISFV 94

  Fly    69 DSELCGRTIRVNLAKPVRVKEDSFKPIWADDDWLQKHAGATLQPEGEPEAEKVETPSTGPAVIEK 133
            :.:..|..:  :|.|            ||.:.|               :...::..:...|:.|.
Human    95 NGQFLGDAL--DLQK------------WAHEVW---------------DIVDIKPSALYDALTED 130

  Fly   134 ------AEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQGYG-------YKG 185
                  .:.::..||.||.|..:..||::..|..||.|||.:||:.|||.:.|:.       ||.
Human   131 FSAKFLRDTKHDFVFLDICIDSSPIGRLIFELYCDVCPKTCKNFQVLCTGKAGFSQRGIRLHYKN 195

  Fly   186 CSFHRVIPEFMCQGGDFTNNNGTGGKSIYG--------------------------KKFNDENFN 224
            ..|||::.....||||.....|..|:||||                          :|:.||||:
Human   196 SIFHRIVQNGWIQGGDIVYGKGDNGESIYGPTFEELYGSLKRSVKRQKESRGVGKIEKYRDENFS 260

  Fly   225 LKHNSFGTLSMANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQ 289
            :.||..|.|.|||.|.::|||||:|....|.:||.|.|.||.:|.|.||::::|...:::..|
Human   261 VPHNKRGVLGMANKGRHSNGSQFYITLQATPYLDRKFVAFGQLIEGTEVLKQLELVPTQNERP-- 323

  Fly   290 KIVIYSC 296
               |:.|
Human   324 ---IHMC 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..82	CDD:409783	14/77 (18%)
		cyclophilin_ABH_like	139..297	CDD:238907	68/191 (36%)
PPIL6	NP_001104768.2	cyclophilin	144..333	CDD:469651	68/189 (36%)