Protein Alignment cyp33 and LOC1270014

DIOPT Version :10

• Sequence 1: NP_523773.1
• Gene: cyp33 / 36984
• FlyBaseID: FBgn0028382
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: XP_308669.2
• Gene: LOC1270014 / 1270014
• VectorBaseID: AGAMI1_001469
• Length: 202
• Species: Anopheles gambiae
• Alignment Length: 963
• Identity: 169/963 - (17%)
• Similarity: 301/963 - (31%)
• Gaps: 318/963 - (33%)

  Fly    63 TPTVPPGSPDQQYQQEGQE--ELANCTEEQEDTGL-----------------QLPVVIIADEVTP 108
            :||:.....::| .|:|.|  ::||........||                 ||.:..::.....
Mosquito    46 SPTLSEPCLEEQ-PQKGTESTDVANTGSSAGSGGLGVLQKFKRTLNNFNNKNQLHISPLSPAAVA 109

  Fly   109 PSVIVEECAEASEVSPTADRGDDESGE---------SSNQR-----NSVEDVGNVEESVR-KLDQ 158
            |.:.....::     |.::.||..||:         ||.:|     |..:...:.:..:: :|:|
Mosquito   110 PMITTTTASD-----PGSEAGDTSSGKYRFGPLIWRSSKERRKTKYNRRDKCNSGDSGIQIELEQ 169

  Fly   159 LEELVIAFYHSCGRRSSRGGADTEQTASEAVRDGA-----SRARAKRTKKRQQQSSGEACTGAYH 218
            .|:.         .|::...:..::..:.|:.:|:     |:.||.|   |...:...:..|.:.
Mosquito   170 DEQY---------SRATMAVSRQDEPRAFALTNGSCGVALSKMRAIR---RTNSAKASSILGPFI 222

  Fly   219 PDQQHQKRHPDPDRTMNQGTDPDQDRDHLAHAAAAATSAPSDTSVVPAGDGRQQAQPQPLRSIHA 283
            ...:..|.       :|.|.....:|       .|..|.|:          |..:||..|.|...
Mosquito   223 VKTKIAKH-------LNIGESDKAER-------KAPESLPT----------RSLSQPNGLESYGM 263

  Fly   284 DAPEPGHSLDRDVPLDDE----------EDTVTLTAETSSECCSQQTVVAVVAEEE-------EV 331
            ..|:...|....|..::|          |.....||....|...::.::..:..:|       .:
Mosquito   264 GRPDLEDSDSDSVASNEEAISFYPTTYAEVLYNFTAGGPQELGLERGMLIEILRKEVGPWWFGRI 328

  Fly   332 EAQAEEVVED--GSSPGHDPTETVAPGSDTTTDD-----EVENDDTGGSDADANDE--------- 380
            :.:...:|||  |...|..|.|.|.......||:     ....|:....:|.|..|
Mosquito   329 KKEETNLVEDILGPELGWFPKEFVRIIHCPETDNFFIAHRAAADEAAAEEATARAEEGSVPVPVA 393

  Fly   381 --AEPGDTC-----TRRTVLGQDSTPSSRRCSLGGEFETEQNRRLR----RRLSELTNNFCTPKQ 434
              ||..|..     :..|::..:|.|:....|:....:.:.:..:|    |.|.:...|:.  |.
Mosquito   394 AFAEDTDVTVTTDQSNVTLIVIESPPTPSAPSVDFVAQPDHSTIIRRSAVRELLDTEVNYV--KL 456

  Fly   435 FQQLCD--------NLDNITDNDLKLLVRELKRKIEFAERMNWLCLSSRPRGPPHR---KTSLPK 488
            ...:||        .:|..:.|.::|:...:....:|..:.    |.:..||....   |..|..
Mosquito   457 LAAICDGYLPAMSKRIDIFSPNSIRLIFSNITAIYKFQRKF----LEALRRGIEQNQVAKVFLKM 517

  Fly   489 HTDVKKRFLETCDKTLSDEVKAALRLPAFDSYEWEDWDVIHLMQTMFVELNLLEKFNIPIVTLRE 553
            |    |.||  |..|..:....||                       :||
Mosquito   518 H----KGFL--CYSTYCNAYPRAL-----------------------IEL--------------- 538

  Fly   554 WLYEVYKHYNDVPFHNYRHCFCVAQMMYTIAWHTNLVQRLGELEV---LVLLVSCICHDLDHPGY 615
               |.|....|.               .||..:....|.|.||.:   |:..|..||.   :|.:
Mosquito   539 ---ETYDRVKDA---------------RTILENCRESQNLAELPLSAHLLAPVQRICR---YPLH 582

  Fly   616 NNIYQINARTELALRYNDISPLENHHCSIAFRLLEHPECNI-----FRNMSKEMYKDVREGIIRC 675
            .|....:|..:.|...||....::...:..:..|:..|.:|     ..|::.|..:.:.|.:
Mosquito   583 LNEIIKSALEKGAKEGNDTDGAKSAGKTTDYEQLDVTELDIPDSQDTVNLALEAMRGITEAV--- 644

  Fly   676 ILATDMARHNEILTQFQ----------------------EATPE--------------------- 697
               .:..||:|.:.:.|                      :||.:
Mosquito   645 ---NEGKRHSETIARHQASFQNFKGPPLHLHSARFFLQVDATRQKQNLWNSSYTLFLFDNQLVYC 706

  Fly   698 ---------FDYSNKVHTNLLCMVLIKVAD-------ISNEAR-PMDVAEPWVDRLLQEFFAQSA 745
                     |.|..::..: .|.| :.|.|       |.|..| ..:..:.|.|     |..:||
Mosquito   707 KRDIIKRSHFIYKGRIFLD-RCRV-VNVRDGKMFGHTIKNSLRIYSESRDKWYD-----FSFRSA 764

  Fly   746 AEKSEGLPVTPFMDPDKVSKPGSQVRFIG-LVLLPLFEALGELLPELTDLIITPVRVALDYYRRL 809
            ..|.                     ||:. |.|...|......:.|:|..       ..:|..|.
Mosquito   765 NRKH---------------------RFLSTLALERQFGGKALYVSEMTGF-------EYNYEERP 801

  Fly   810 NDAANKTRRSIAEAEAASSESGGSPQLPRSQSGISVKSRRSIPSQKSASRTSV 862
            .|.::::.....:.|.|:..:.|...||.|.:..:.:...::| :||.||..:
Mosquito   802 GDYSDQSDYDAQDFELATGVTSGESSLPESPAKSTSRLCETLP-KKSQSRDGI 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..82	CDD:409783	6/20 (30%)
		cyclophilin_ABH_like	139..297	CDD:238907	28/168 (17%)
LOC1270014	XP_308669.2	cyclophilin	25..185	CDD:469651	26/153 (17%)