Protein Alignment cyp33 and PPIE

DIOPT Version :9

• Sequence 1: NP_523773.1
• Gene: cyp33 / 36984
• FlyBaseID: FBgn0028382
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_001181936.1
• Gene: PPIE / 10450
• HGNCID: 9258
• Length: 314
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 187/281 - (66%)
• Similarity: 226/281 - (80%)
• Gaps: 5/281 - (1%)

  Fly     1 MSNDKRTIYVGGLADEVTERLLNNAFIPFGDIADIQMPADYESQRHRGFAFIEYEQSEDAAAAID 65
            |:..||.:||||||:||.:::|:.||||||||.|||:|.|||:::||||||:|:|.:||||||||
Human     1 MATTKRVLYVGGLAEEVDDKVLHAAFIPFGDITDIQIPLDYETEKHRGFAFVEFELAEDAAAAID 65

  Fly    66 NMNDSELCGRTIRVNLAKPVRVKEDSFKPIWADDDWLQKHAGATLQPEGEPEAE---KVETPSTG 127
            |||:|||.|||||||||||:|:||.|.:|:|:|||||:|.:|.||:...|.|..   |.||....
Human    66 NMNESELFGRTIRVNLAKPMRIKEGSSRPVWSDDDWLKKFSGKTLEENKEEEGSEPPKAETQEGE 130

  Fly   128 PAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAENFRQLCTHEQGYGYKGCSFHRVI 192
            |  |.|..:.||||:.||:||...||||.||||:||||.||||||.|||||:|:|:||.||||:|
Human   131 P--IAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPMTAENFRCLCTHEKGFGFKGSSFHRII 193

  Fly   193 PEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSMANSGANTNGSQFFICTTKTDWL 257
            |:||||||||||:|||||||||||||:||||.|||...|.|||||||.||||||||:...|||||
Human   194 PQFMCQGGDFTNHNGTGGKSIYGKKFDDENFILKHTGPGLLSMANSGPNTNGSQFFLTCDKTDWL 258

  Fly   258 DNKHVVFGHVISGAEVVRKME 278
            |.||||||.|..|.:|:|::|
Human   259 DGKHVVFGEVTEGLDVLRQIE 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793	51/71 (72%)
		cyclophilin_ABH_like	139..297	CDD:238907	103/140 (74%)
PPIE	NP_001181936.1	RRM	<5..>84	CDD:223796	57/78 (73%)
		RRM_PPIE	8..80	CDD:240793	51/71 (72%)
		cyclophilin_ABH_like	140..279	CDD:238907	102/138 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2341
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38142
Inparanoid	1	1.050	413	1.000	Inparanoid score	I1859
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1484092at2759
OrthoFinder	1	1.000	-	-		FOG0004615
OrthoInspector	1	1.000	-	-		oto91411
orthoMCL	1	0.900	-	-		OOG6_106441
Panther	1	1.100	-	-	LDO	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4943
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.830