DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyp33 and PPIF

DIOPT Version :9

Sequence 1:	NP_523773.1	Gene:	cyp33 / 36984	FlyBaseID:	FBgn0028382	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_005720.1	Gene:	PPIF / 10105	HGNCID:	9259	Length:	207	Species:	Homo sapiens

Alignment Length:	194	Identity:	119/194 - (61%)
Similarity:	140/194 - (72%)	Gaps:	14/194 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 AGATLQPEGEPEAEKVETPSTGPAVIEKAEKRNPQVFFDIRIGGNDAGRIVMLLRADVVPKTAEN 170
            |.|..:..|:|.:    :.|:|          ||.|:.|:...|...||:|:.|:||||||||||
Human    27 ARACSKGSGDPSS----SSSSG----------NPLVYLDVDANGKPLGRVVLELKADVVPKTAEN 77

  Fly   171 FRQLCTHEQGYGYKGCSFHRVIPEFMCQGGDFTNNNGTGGKSIYGKKFNDENFNLKHNSFGTLSM 235
            ||.|||.|:|:||||.:||||||.||||.|||||:||||||||||.:|.||||.|||...|.|||
Human    78 FRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSM 142

  Fly   236 ANSGANTNGSQFFICTTKTDWLDNKHVVFGHVISGAEVVRKMERCGSKSGTPSQKIVIYSCGEL 299
            ||:|.|||||||||||.||||||.||||||||..|.:||:|:|..|||||..|:||||..||:|
Human   143 ANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRTSKKIVITDCGQL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyp33	NP_523773.1	RRM_PPIE	8..80	CDD:240793
cyp33	NP_523773.1	cyclophilin_ABH_like	139..297	CDD:238907	109/157 (69%)
PPIF	NP_005720.1	cyclophilin_ABH_like	46..204	CDD:238907	109/157 (69%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D563773at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820