Protein Alignment eIF3b and eIF3b

DIOPT Version :10

• Sequence 1: NP_611228.1
• Gene: eIF3b / 36981
• FlyBaseID: FBgn0034237
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: XP_061511748.1
• Gene: eIF3b / 1280537
• VectorBaseID: AGAMI1_007165
• Length: 689
• Species: Anopheles gambiae
• Alignment Length: 663
• Identity: 461/663 - (69%)
• Similarity: 539/663 - (81%)
• Gaps: 15/663 - (2%)

  Fly     1 MAKKKSEEHSGTDANDSDYQEEPNFDDPPGFVDNISDEDLLGDMLAQRPSEADGVESVVVVDNIP 65
            |||||.|        |.|::||||||||.||||::|||:||||.|.|:|.|:||||:|:||||||
Mosquito     1 MAKKKGE--------DQDFEEEPNFDDPEGFVDDVSDEELLGDFLRQKPCESDGVENVIVVDNIP 57

  Fly    66 KVEPVRLEKLKLVINKLFSNYGEIVNVVYPVDEEGKTKGYAFMEYKQARQAEEAVKKLNNHRLDK 130
            .|...|..|||.:|.|:|.|.|.||||.||.|||..||||||:|||....||||||.|||:||||
Mosquito    58 VVGAARFPKLKGIIEKIFKNAGTIVNVHYPKDEEDNTKGYAFVEYKNQESAEEAVKSLNNYRLDK 122

  Fly   131 NHTFAVNLFTDFQKYENIPEKWEPPTVQTFKVQSDLYNFINDPDTYDQYCVAAETAPNCVQVGFW 195
            ::|..||.|.|||||.:||::|.||..|.:|||:|||||:.:.|..||:||.:||.|..|||.|.
Mosquito   123 HYTLLVNRFADFQKYSDIPKEWSPPQPQPYKVQNDLYNFLLEADAQDQFCVVSETVPGSVQVQFC 187

  Fly   196 QNVLPEPFELETRERFTDTFVKWSPLGTYVVTFHKPGVAIWGGSSFQKIQKFPHPGTQFVEFSPC 260
            ||..|||.||..|||||||:|||||.|||:|||||.||.:||||||.|:.||.|...|||:.|||
Mosquito   188 QNTQPEPTELLKRERFTDTYVKWSPKGTYIVTFHKQGVVVWGGSSFVKVNKFAHSNAQFVDISPC 252

  Fly   261 ENYLVTYGPTPTGQKIIIWDIRTGAEKRSFVADGMSVLSMFRWSHDDKFVARMGENSIHIYETPS 325
            |.||||||  |.||||:|||||||||||:||:||||..||.||||||::|||:.::.|.||:|.:
Mosquito   253 EQYLVTYG--PNGQKIVIWDIRTGAEKRTFVSDGMSNASMLRWSHDDRYVARLVDSQIQIYDTTT 315

  Fly   326 FYLLDLKSIKIPGIRGFSWSPTDNVIAYWVEEQNQIPARVTLMEIPKKREIRNKNLFHVADCKLH 390
            |:|||:|||::.|||.||||||||:|||||.|:..:||:||||.||||.|:|.||||:|||||:|
Mosquito   316 FFLLDMKSIRVEGIRNFSWSPTDNIIAYWVAEEVDVPAKVTLMAIPKKTELRTKNLFNVADCKIH 380

  Fly   391 WQKSGDYLCVKVDRYSKL---KKDKKDLDVKFLGMFYNFEIFHMREKEIPVDSVEIRELILAFAW 452
            ||||||||||||||:||.   ||||||.|||||||||||||||||||:|||||||::|.||||||
Mosquito   381 WQKSGDYLCVKVDRFSKSKKEKKDKKDSDVKFLGMFYNFEIFHMREKDIPVDSVEVKETILAFAW 445

  Fly   453 EPVGNKFSIIHGETNSSNVSFYEVNKGVKPSLVKRLEKKSCTHLFWSPRGQFIVMANLTMGTFEF 517
            ||||:||||||||.:|:||||||.|||.:|.|||:||||.|.||||||||||||:|||.||||||
Mosquito   446 EPVGSKFSIIHGEPSSANVSFYETNKGQEPVLVKKLEKKVCGHLFWSPRGQFIVLANLQMGTFEF 510

  Fly   518 VDSTNDYIITASPDHFRASEVEWDPTGRYVVTGVSSWKVKEDTGFNMYTFQGRIIKRTILKNFVQ 582
            || |||:.|..:.||:|||||||||||||||||.|. |.|||.|:.|::|||||:||..||||:.
Mosquito   511 VD-TNDFSIMKTGDHYRASEVEWDPTGRYVVTGTSG-KAKEDQGYYMWSFQGRILKRVNLKNFML 573

  Fly   583 FLWRPRPPTLLSEEKQKEIKKNLKKYYAAFEQKDRLRLTRASKELLEKRSQLRETFMEYRNKRIA 647
            ||||||||||||:.|||||.|||||||:.||.|||||:|||||||:|||::|||.|.|||:||:.
Mosquito   574 FLWRPRPPTLLSDAKQKEILKNLKKYYSQFESKDRLRMTRASKELIEKRAKLREQFTEYRSKRVK 638

  Fly   648 EWAEQKSRRIMLR 660
            ||.:||.||:.||
Mosquito   639 EWEDQKKRRMQLR 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3b	NP_611228.1	RRM_eIF3B	56..137	CDD:409720	50/80 (63%)
		COG5354	194..690	CDD:227657	344/470 (73%)
eIF3b	XP_061511748.1	None