Protein Alignment Patronin and camsap3

DIOPT Version :9

• Sequence 1: NP_001261051.1
• Gene: Patronin / 36978
• FlyBaseID: FBgn0263197
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: XP_002941532.2
• Gene: camsap3 / 100124982
• XenbaseID: XB-GENE-5845672
• Length: 1332
• Species: Xenopus tropicalis
• Alignment Length: 1829
• Identity: 386/1829 - (21%)
• Similarity: 631/1829 - (34%)
• Gaps: 658/1829 - (35%)

  Fly     3 VETQEIRQARQRASVKWLLSKAFNNRVPDNLKEPFYRDHENQERLKPQIIVELGNATLYCQTLAN 67
            ::..:::|||..||:.||:.:.:...||..|..|.|.|...||.:||..|..|.:|.:||:....
 Frog     8 LDVYDVQQARISASLSWLIYRYYGKEVPAELCSPCYTDQYEQEHVKPAAIALLLSADIYCRAYRR 72

  Fly    68 LYSDPNYQSMNHWSIIQTLARKGVPVAESADMPITETVLIQTNPLRINAHMSVIESLMVLYA--- 129
            .....:....::..::..|||||:......: |: :|..::..|:|:.||:::|:|||.||:
 Frog    73 ALPHDSSPPRDNAGLLLMLARKGLAPTNQGE-PV-KTSDLREKPIRMAAHLALIDSLMTLYSIHC 135

  Fly   130 -------KEISSGD---RVMAAIRRISGNNY--------------QAPTGQSYEQALLGW----I 166
                   .|||...   :::..|.::  ||:              .||.||:.......|    :
 Frog   136 TAPLPPDAEISLTSVETKLLDWIDKV--NNHLLDEAEREQGKKQMSAPEGQNQAGCPSRWYWKLV 198

  Fly   167 SHACA-ALKKRIIKEVDAGLPDDNGSRLQTPDIPPVRDFQDLCDGICLALLISYYCPKVVPWTSV 230
            .||.| .||:...|........|.....|||....|...:||.:|..||..:.||||..:....:
 Frog   199 PHAIAFCLKESGNKPPVIRYRKDKALSRQTPCFTAVSSLRDLSNGSALAATVHYYCPAQLRLQDI 263

  Fly   231 RINYLPAVEDSIHNILLVCNFSQKHLPYTVMHMTPEDVTYMRGSMKLNLVVLLTDLFNLFEIHPA 295
            .:....:|.||::|:.|:..|..:|||.: ..::.||:.|:..::|:|||.||.||:..||:...
 Frog   264 CLKDTMSVADSLYNLQLLREFYAQHLPPS-CPLSLEDLLYVPSALKVNLVALLADLYLCFEVAKP 327

  Fly   296 KCV----CYPGMDGQVPHSNSFGG-----GLNRRSTPPNEYQTVQSNNFDGNHAEAFVVHKSRGI 351
            ..|    .|...:...|.|...||     ..||   |.|......|::.  :|.|.|
 Frog   328 DFVQPKDVYLHSESATPSSAHSGGRSPVFNFNR---PGNTGSLPHSSSM--SHMEGF-------- 379

  Fly   352 TTLASMHSQQQQQLHQQQQHQQQYHQQPLQQHPSQSQLQIQQQEPLVPARLRQAKEKTNVESKAD 416
                                .:.:.:.|| .||....:...     :|..|         :|..|
 Frog   380 --------------------GKAWVKNPL-SHPLSQAVSFS-----IPFGL---------DSDVD 409

  Fly   417 ERGDFVAAGRPSNWEQS-------------RRPSFAGRRS-----------------RRNSSSED 451
                 :..|.|.|..:|             :.||...|.:                 .:.:|..:
 Frog   410 -----IVMGNPVNIMRSVSSDSLNPPAFPPKSPSCVSRATYTPPEDAAELRTLKKVPGKVTSDLN 469

  Fly   452 SQLTIENFGGSQDQLNTLGR-----YERDRERKLSNTSVGSYPVEPAVAVRSSIADARGTLQLG- 510
            ||.......|.|..|.|:..     :..:..........|.|...|..|....:.:...|..:|
 Frog   470 SQDKTAGSPGVQSDLPTIEEALQIIHSSEARHLPDGAPDGFYLHSPEEAKPPKVEELVVTPNVGV 534

  Fly   511 YDTDSGSEKQDRETEKYSMRRQVSVDNVPTVSSHNLSNAGSPLPV--ARHKQHSSDKDYSSNSG- 572
            |.|.:.|.:..|:.:  |:.|..|:|          |:|....|.  :.....||..|.|:..|
 Frog   535 YRTHNASRRLSRDDD--SVLRDNSLD----------SDAEETKPAQDSSRSSLSSQADSSTGPGT 587

  Fly   573 -MTPDAYNDSRSTSGYDPESTPVRKSSTSSMPA-SP--AAWQLDVGDDDMRSLENASKLSTIRMK 633
             ||..|....:..:...||.:|      ||:|. ||  ..|.....:..::|....|:::.:..:
 Frog   588 KMTSFAEKKKKINAKATPEGSP------SSLPLNSPNTTTWAQKAEESPVKSPALNSEMNQLSAR 646

  Fly   634 LEEKRRRIEQDKRKIEMALLRHQEK-------------------EDLESCPDVMKWETMSNESKR 679
            |||||:.||..|::||....:|:::                   |:.:..||....:.:.:|.:|
 Frog   647 LEEKRKAIEAQKKRIEAIFAKHRQRLGKSAFLQLNKKDGEEGEVEEGKLSPDEGLPKELDDEGRR 711

  Fly   680 ---------------------------TPDMDPVDLDK----YQQSIAIMNMNLQDIQQDIHRLA 713
                                       :||:....||.    |.:::|.:|..|..:|.|:.||:
 Frog   712 KQFSEDENNDEKSDVVMRPRVEKQVSFSPDVAKEGLDNNLGDYNRAVAKLNNALSSLQSDMKRLS 776

  Fly   714 TQQSQMQAQHLQAQQLMQAQQIANMLNQQQTYGSQQHLADHHYQQQRPMQQSFGSSPHLPQAYNA 778
            .||.:|..:..:|..:                               |..:: ...||.|:
 Frog   777 DQQDKMMKKESKAWVI-------------------------------PAPKA-SPPPHRPK---- 805

  Fly   779 PVSAYSSRPPSRDPYQQQLHHQQQQPMPMPQPMQYVNEHGQYMSPPQPAHYMPQQAQQPQSIYSD 843
                  |.||.|                                       :.::.|.|:|....
 Frog   806 ------SSPPVR---------------------------------------LTREIQAPRSSLPA 825

  Fly   844 NGAAYNHSNHSPYGGTPQYRSSVVYDDYGQPTNHFYLHESSPQPQAHQHPQRRTWAHSAAAAAYE 908
            :      .:|||....|:                      ||||.|     ||::
 Frog   826 S------PSHSPSRFVPK----------------------SPQPNA-----RRSY---------- 847

  Fly   909 QQQQIQPSLVDVNAWQTQQHQKQKQTWMNRPPSSAGAPSPGSFMLHQNGGGGGGGGGGGELQHLF 973
                 ||..:
 Frog   848 -----QPVPI------------------------------------------------------- 852

  Fly   974 QVQASPQHGQRQVSGSNGVQRQQSLTNLRDNRSPKAPQ-NMGMPMGMPMQQEDMMAPQSICFIGD 1037
                                            :||:|: |..:.:.:|.....:..|.::..|
 Frog   853 --------------------------------TPKSPKTNRPVELKLPPVNRVLTLPHNVDTI-- 883

  Fly  1038 EEDVDELERNIIESMQSTHISDFVHQQQQQHQHQQQLQQQQRLQGHSGRGSSSEDYDSGEMISNK 1102
                             .|:..|                           |.|
 Frog   884 -----------------PHLRKF---------------------------SPS------------ 892

  Fly  1103 LNITSGNLTYRIPSPSRPSIQANSFQDPRAMAAASGGEDQPPEKGFYISFDDEQPKRPKPPLRAK 1167
                      ::|..::.||    :...:.:.....||..|..:|
 Frog   893 ----------KVPDQTKTSI----YVTHKGLEGEEDGETVPAVEG-------------------- 923

  Fly  1168 RSPKKESPPGSRDSVDNQATLKRESLSHLHNNNNIGFGNDDVNSKPVTRHSIHGLNNSNSVKSPG 1232
                                         |.           |.:||.         |...:|.|
 Frog   924 -----------------------------HG-----------NMRPVA---------SVVPQSSG 939

  Fly  1233 NATYNKYTDEPPIQLRQLAVSGAMSPTSNERHHLDDVSNQSPQQTQQPMSPTRLQQSSNNAEAAK 1297
            .|.:.:.|:.....|.::.:|        :....:|...:.|...:.......||:....
 Frog   940 VAPWTEETESKRSSLIEIPLS--------DLRAAEDSETEGPDSLEGTPGEDELQRGGVG----- 991

  Fly  1298 NKALVIGADSTNLDPESVDEMERRKEKIMLLSLQRRQQQ-EEAKARKEIEASQKREKE-----RE 1356
              ....|.:.|.      |||.:|:..:    |:::|:: ||||.||:.:..:|.:||     ::
 Frog   992 --FFFKGEERTE------DEMAQRRAAL----LEKQQKRTEEAKKRKQWQEEEKEKKEEASRQQQ 1044

  Fly  1357 KEEERARKKEEQMARRAAILE---QHRLKKAIEEAEREGKTLDRPDLHVKLQSHSSTSTTPRLRQ 1418
            ::||:.||:||.:|||.....   :.||:..|.|      .||:.                 |||
 Frog  1045 QQEEQKRKEEEVVARRGDFTRKEYERRLQLKIME------DLDKV-----------------LRQ 1086

  Fly  1419 QRTT-----RPRPKTIHVDDASVDISEASSISSRGKKGSSSNLTGYGQLSSNSMKRDYYRGSQDS 1478
            :..|     :|||||:..||:.:..|..     ||..||        :||.      .|..|..|
 Frog  1087 KPMTVRAVKKPRPKTVFRDDSVISRSPV-----RGLLGS--------KLSK------VYSQSTMS 1132

  Fly  1479 LTVKDSGLGRATPPRRAPSPGMGMGASGRHMPSPSGPGSLPPGLISKRRGFDDGSSDFSLTPNLN 1543
            |:...:..|.:|..:...||        |.| ||.||.|...|..::....|..::..:.:|...
 Frog  1133 LSTVGNESGFSTMKKSPKSP--------RAM-SPCGPMSPIKGTFAQNGDKDWDAASTASSPASI 1188

  Fly  1544 MEYSGPKLYKQPAAKSNRGIILNAVEYCVFPGVVNREAKQKVLEKIARSEAKHFLVLFRDAGCQF 1608
            .||:||:|||:|:||||:.||.||:.:|...|.||...|.||||.:.:|.|.|||:||||..|||
 Frog  1189 PEYTGPRLYKEPSAKSNKFIIHNALSHCCLAGKVNESQKIKVLEDMEKSPANHFLILFRDNSCQF 1253

  Fly  1609 RALYSYQPETDQVTKLYGTGPSQVEEVMFDKFFKYNSGGKCFSQVHTKHLTVTIDAFTIHNSLWQ 1673
            ||:|::..||:::::|.|.||..:...|.:..:||:|..|.|:|:.:|.:::::|||||....||
 Frog  1254 RAVYAFSAETEELSRLAGIGPRTISLAMIEDIYKYSSDRKRFTQIPSKTMSMSVDAFTIQGHHWQ 1318

  Fly  1674 GKRVQLPSK 1682
            .||...|.|
 Frog  1319 SKRPTTPKK 1327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Patronin	NP_001261051.1	CAMSAP_CH	189..272	CDD:288798	25/82 (30%)
		CAMSAP_CC1	612..679	CDD:293700	17/85 (20%)
		tolA_full	1271..>1391	CDD:274303	33/128 (26%)
		CAMSAP_CKK	1549..1667	CDD:285846	54/117 (46%)
camsap3	XP_002941532.2	CAMSAP_CH	225..304	CDD:314792	25/79 (32%)
		CAMSAP_CC1	625..683	CDD:374981	13/57 (23%)
		PTZ00449	<785..980	CDD:185628	56/559 (10%)
		CAMSAP_CKK	1194..1312	CDD:370058	54/117 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5008
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2078
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324856at33208
OrthoFinder	1	1.000	-	-		FOG0001093
OrthoInspector	1	1.000	-	-		otm48466
Panther	1	1.100	-	-	O	PTHR21595
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X931
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160