DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4866 and C48B6.2

DIOPT Version :9

Sequence 1:	NP_611224.1	Gene:	CG4866 / 36976	FlyBaseID:	FBgn0034232	Length:	181	Species:	Drosophila melanogaster
Sequence 2:	NP_491972.1	Gene:	C48B6.2 / 172420	WormBaseID:	WBGene00016740	Length:	183	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	90/181 - (49%)
Similarity:	130/181 - (71%)	Gaps:	0/181 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVRKLKFHEQKLLKKVDFITWKVDNGGKENKILRRFHIQKREDYTKYNKLSREIRELAERIAKLD 65
            ||||||.||||||||.||::|:||..||:..:||:|:::|||.|..||.|:.:.||:|:.|..|.
Worm     1 MVRKLKTHEQKLLKKTDFMSWQVDQQGKQGDMLRKFYVKKREHYALYNTLAAKSREVADLIKNLS 65

  Fly    66 ASEPFKTEATTMLLNKLHAMGVSNDQLTLETAAKISASHFCRRRLPVIMVKLRMSEHLKAATDLI 130
            .|:||:::.|..:|.|.:|.|:.....|||...|::.:.|.||||||:|..:.|.|.:|.|:||:
Worm    66 ESDPFRSKCTEDMLTKFYAAGLVPTSDTLERIGKVTGASFARRRLPVVMRNIGMCESVKTASDLV 130

  Fly   131 EHGHVRVGPEMIKDPAFLVSRNLEDFVTWVDGSKIKEHVLRYNDMRDDFQM 181
            |.||||:|.:::.||||:|:|:.||.:||...||||:||:.||:.||||.:
Worm   131 EQGHVRIGTKLVTDPAFMVTRSSEDMITWTKASKIKKHVMDYNNTRDDFDL 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4866	NP_611224.1	RpsD	1..>166	CDD:223596	80/164 (49%)
CG4866	NP_611224.1	S4	108..154	CDD:279780	24/45 (53%)
C48B6.2	NP_491972.1	RpsD	1..>167	CDD:223596	81/165 (49%)
C48B6.2	NP_491972.1	S4	108..157	CDD:279780	26/48 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167787
Domainoid	1	1.000	72	1.000	Domainoid score	I6087
eggNOG	1	0.900	-	-		E1_COG0522
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6120
Inparanoid	1	1.050	196	1.000	Inparanoid score	I2516
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53817
OrthoDB	1	1.010	-	-		D1336285at2759
OrthoFinder	1	1.000	-	-		FOG0004591
OrthoInspector	1	1.000	-	-		oto19767
orthoMCL	1	0.900	-	-		OOG6_102070
Panther	1	1.100	-	-	LDO	PTHR11831
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R609
SonicParanoid	1	1.000	-	-		X3205
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840