DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4866 and Imp3

DIOPT Version :9

Sequence 1:	NP_611224.1	Gene:	CG4866 / 36976	FlyBaseID:	FBgn0034232	Length:	181	Species:	Drosophila melanogaster
Sequence 2:	NP_598737.1	Gene:	Imp3 / 102462	MGIID:	1916119	Length:	184	Species:	Mus musculus

Alignment Length:	182	Identity:	106/182 - (58%)
Similarity:	144/182 - (79%)	Gaps:	1/182 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVRKLKFHEQKLLKKVDFITWKV-DNGGKENKILRRFHIQKREDYTKYNKLSREIRELAERIAKL 64
            ||||||||||||||:|||:.|:| |:...|.::|||:.:|:||:||:||:|||.:||||.|:..|
Mouse     1 MVRKLKFHEQKLLKQVDFLNWEVTDHNLHELRVLRRYRLQRREEYTRYNQLSRAVRELARRLRDL 65

  Fly    65 DASEPFKTEATTMLLNKLHAMGVSNDQLTLETAAKISASHFCRRRLPVIMVKLRMSEHLKAATDL 129
            ...:||:..|:..||:||:|||:...:.:||....:|||.|||||||.:::||||::||:||...
Mouse    66 PERDPFRVRASAALLDKLYAMGLVPTRGSLELCDSVSASSFCRRRLPTLLLKLRMAQHLQAAVAF 130

  Fly   130 IEHGHVRVGPEMIKDPAFLVSRNLEDFVTWVDGSKIKEHVLRYNDMRDDFQM 181
            :|.|||||||:::.||||||:|::||||||||.||||.|||.||:.||||.:
Mouse   131 VEQGHVRVGPDVVTDPAFLVTRSMEDFVTWVDSSKIKRHVLEYNEERDDFDL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4866	NP_611224.1	RpsD	1..>166	CDD:223596	95/165 (58%)
CG4866	NP_611224.1	S4	108..154	CDD:279780	27/45 (60%)
Imp3	NP_598737.1	RpsD	1..>168	CDD:223596	96/166 (58%)
Imp3	NP_598737.1	S4	109..155	CDD:279780	27/45 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850708
Domainoid	1	1.000	79	1.000	Domainoid score	I8706
eggNOG	1	0.900	-	-		E1_COG0522
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6120
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3468
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53817
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004591
OrthoInspector	1	1.000	-	-		oto92865
orthoMCL	1	0.900	-	-		OOG6_102070
Panther	1	1.100	-	-	LDO	PTHR11831
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R609
SonicParanoid	1	1.000	-	-		X3205
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790