DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment APC10 and Anapc10

DIOPT Version :9

Sequence 1:	NP_611223.4	Gene:	APC10 / 36975	FlyBaseID:	FBgn0034231	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001344163.1	Gene:	Anapc10 / 68999	MGIID:	1916249	Length:	185	Species:	Mus musculus

Alignment Length:	186	Identity:	106/186 - (56%)
Similarity:	140/186 - (75%)	Gaps:	12/186 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PPSSEEDPLAEERLGFVREVGAQAVWSLSSCKPGFGVERLRDNIMDTYWQSDGQLPHLVNIQFHK 78
            ||.:  ||...||...|||:|:|||||||||||||||::|||:.::|||||||..||||||||.:
Mouse     8 PPGA--DPKQLERTATVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRR 70

  Fly    79 RTNISQIYIYTDYKLDESYTPSRISIRSGTNFNDLQELQVMDLTEPTGWVQIPIKDGNVKSIRTF 143
            :|.:..:.||.|||.|||||||:||:|.|.||::|||::.::|.||:||:.:|:.|.:.|..|||
Mouse    71 KTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTF 135

  Fly   144 MLQIAVISNHQNGRDTHMRQIRIHAPVE----GKHYPLELFGKFGTVDFQKFATIR 195
            |:||||::|||||||||||||:|:.|||    ||      |.:..|:||..:.:||
Mouse   136 MIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGK------FPRCTTIDFMMYRSIR 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
APC10	NP_611223.4	ANAPC10	10..193	CDD:367420	104/182 (57%)
Anapc10	NP_001344163.1	ANAPC10	4..183	CDD:367420	104/182 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846725
Domainoid	1	1.000	220	1.000	Domainoid score	I2600
eggNOG	1	0.900	-	-		E1_COG5156
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32238
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3500
Isobase	1	0.950	-	0	Normalized mean entropy	S1484
OMA	1	1.010	-	-		QHG54580
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004014
OrthoInspector	1	1.000	-	-		oto94491
orthoMCL	1	0.900	-	-		OOG6_102604
Panther	1	1.100	-	-	LDO	PTHR12936
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R66
SonicParanoid	1	1.000	-	-		X3299
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740