DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4847 and RD21A

DIOPT Version :9

Sequence 1:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_564497.1	Gene:	RD21A / 841122	AraportID:	AT1G47128	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	275	Identity:	112/275 - (40%)
Similarity:	151/275 - (54%)	Gaps:	25/275 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 TFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKF 220
            :::..:..|||||:.|:.|:..|.|.  |.|.....||:........:|::.|||:.|.|..||.
plant    92 SYRLGLTRFADLTNDEYRSKYLGAKM--EKKGERRTSLRYEARVGDELPESIDWRKKGAVAEVKD 154

  Fly   221 QGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLN-GCDGGFQEAAFCFIDEV 284
            ||.|||||||:|.||:||.....||.|..||||.||||    |...| ||:||..:.||.||.:
plant   155 QGGCGSCWAFSTIGAVEGINQIVTGDLITLSEQELVDC----DTSYNEGCNGGLMDYAFEFIIK- 214

  Fly   285 QKGVSQEGAYPYIDNKGTCKYDGSKSGA---TLQGFAAIPPKDEEQLKKVVATLGPVACSVN-GL 345
            ..|:..:..|||....|||  |..:..|   |:..:..:|...||.|||.||. .|::.::. |.
plant   215 NGGIDTDKDYPYKGVDGTC--DQIRKNAKVVTIDSYEDVPTYSEESLKKAVAH-QPISIAIEAGG 276

  Fly   346 ETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPR------ 404
            ...:.|..||: |..|.. :.:|.::.||||:|.|:|||||:|||..:|||.||.|:.|
plant   277 RAFQLYDSGIF-DGSCGT-QLDHGVVAVGYGTENGKDYWIVRNSWGKSWGESGYLRMARNIASSS 339

  Fly   405 GKNYCFIAEECSYPV 419
            ||  |.||.|.|||:
plant   340 GK--CGIAIEPSYPI 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	5/15 (33%)
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	97/224 (43%)
RD21A	NP_564497.1	Inhibitor_I29	50..107	CDD:214853	5/14 (36%)
		Peptidase_C1	137..352	CDD:395062	98/226 (43%)
		GRAN	376..432	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780