DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4847 and RD21B

DIOPT Version :9

Sequence 1:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_568620.1	Gene:	RD21B / 834321	AraportID:	AT5G43060	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	300	Identity:	116/300 - (38%)
Similarity:	158/300 - (52%)	Gaps:	53/300 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 STKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTG-------LKRSPEAKARAAASLKL 195
            :||||             ::|..:..|||||:.|:.|...|       ||.|...:||...:|
plant    89 NTKNL-------------SYKLGLTRFADLTNEEYRSMYLGAKPTKRVLKTSDRYQARVGDAL-- 138

  Fly   196 VNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGP 260
                    ||:.|||:.|.|..||.||:|||||||:|.||:||.....||.|.:||||.||||
plant   139 --------PDSVDWRKEGAVADVKDQGSCGSCWAFSTIGAVEGINKIVTGDLISLSEQELVDC-- 193

  Fly   261 VEDFGLN-GCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYDGSKSGA---TLQGFAAIP 321
              |...| ||:||..:.||.||.: ..|:..|..|||....|.|  |.::..|   |:..:..:|
plant   194 --DTSYNQGCNGGLMDYAFEFIIK-NGGIDTEADYPYKAADGRC--DQNRKNAKVVTIDSYEDVP 253

  Fly   322 PKDEEQLKKVVATLGPVACSVN-GLETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWI 385
            ...|..|||.:|. .|::.::. |....:.|:.|:: |..|.. |.:|.::.||||:|.|:||||
plant   254 ENSEASLKKALAH-QPISVAIEAGGRAFQLYSSGVF-DGLCGT-ELDHGVVAVGYGTENGKDYWI 315

  Fly   386 VKNSWDDTWGEKGYFRL------PRGKNYCFIAEECSYPV 419
            |:|||.:.|||.||.::      |.||  |.||.|.|||:
plant   316 VRNSWGNRWGESGYIKMARNIEAPTGK--CGIAMEASYPI 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	10/33 (30%)
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	95/224 (42%)
RD21B	NP_568620.1	Inhibitor_I29	50..109	CDD:214853	10/32 (31%)
		Peptidase_C1	138..353	CDD:278538	97/236 (41%)
		GRAN	377..433	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780