Protein Alignment CtsK2 and Ctsll3

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_081620.2
• Gene: Ctsll3 / 70202
• MGIID: 1917452
• Length: 331
• Species: Mus musculus
• Alignment Length: 335
• Identity: 127/335 - (37%)
• Similarity: 190/335 - (56%)
• Gaps: 22/335 - (6%)

  Fly    93 VGNIAKAVPKVPLLSNVQDFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTF 157
            :|.::.|....|.|..|.:  ::.::..||| :..|.......:.:.|.:::..|..:.:|.|.|
Mouse    12 LGVVSAAPAHNPSLDAVWE--EWKTKHKKTY-NMNDEGQKRAVWENNKKMIDLHNEDYLKGKHGF 73

  Fly   158 KQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLP-AKPIPDAFDWREHGGVTPVKFQ 221
            ...:|||.|||::||...:||.:..     :....:|:...| ...:|.:.|||:||.|||||.|
Mouse    74 SLEMNAFGDLTNTEFRELMTGFQGQ-----KTKMMMKVFQEPLLGDVPKSVDWRDHGYVTPVKDQ 133

  Fly   222 GTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQK 286
            |:|||||||:..|::||..|||||.|..||.||||||...:  |..|||||..:.||.::.: ..
Mouse   134 GSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQ--GNQGCDGGLPDLAFQYVKD-NG 195

  Fly   287 GVSQEGAYPYIDNKGTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLET---- 347
            |:....:|||....|||:|:...|.||:.||..: ...|:.|.|.|||:||::.   |::|
Mouse   196 GLDTSVSYPYEALNGTCRYNPKNSAATVTGFVNV-QSSEDALMKAVATVGPISV---GIDTKHKS 256

  Fly   348 LKNYAGGIYNDDECNKGEPNHSILVVGYGSEK-GQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCF 410
            .:.|..|:|.:.:|:....:|::||||||.|. |:.||:|||||...||..||.::.:.: |.|.
Mouse   257 FQFYKEGMYYEPDCSSTVLDHAVLVVGYGEESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCG 321

  Fly   411 IAEECSYPVV 420
            ||.:.|||||
Mouse   322 IASDASYPVV 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	15/59 (25%)
		Peptidase_C1A	204..418	CDD:239068	97/219 (44%)
Ctsll3	NP_081620.2	Inhibitor_I29	29..87	CDD:214853	15/60 (25%)
		Peptidase_C1	115..330	CDD:425470	98/221 (44%)