Protein Alignment CtsK2 and Ctsm

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_071721.2
• Gene: Ctsm / 64139
• MGIID: 1927229
• Length: 333
• Species: Mus musculus
• Alignment Length: 307
• Identity: 113/307 - (36%)
• Similarity: 156/307 - (50%)
• Gaps: 16/307 - (5%)

  Fly   120 GKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPE 184
            ||.| |..:.......:......::..|.....|.|.|...:|||.|:|..||...:..:.....
Mouse    37 GKAY-SLEEEGQKRAVWEDNMKKIKLHNGENGLGKHGFTMEMNAFGDMTLEEFRKVMIEIPVPTV 100

  Fly   185 AKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPN 249
            .|.::......|||     |...:|::.|.||||:.||.|.|||||:.||||||..|||||.|..
Mouse   101 KKGKSVQKRLSVNL-----PKFINWKKRGYVTPVQTQGRCNSCWAFSVTGAIEGQMFRKTGQLIP 160

  Fly   250 LSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYDGSKSGATL 314
            ||.||||||...:  |..||..|....|..::.| ..|:..|..|||.:..|:|:|....|.|.:
Mouse   161 LSVQNLVDCSRPQ--GNWGCYLGNTYLALHYVME-NGGLESEATYPYEEKDGSCRYSPENSTANI 222

  Fly   315 QGFAAIPPKDEEQLKKVVATLGPVACSVNGLE-TLKNYAGGIYNDDECNKGEPNHSILVVGYG-- 376
            .||..: ||:|:.|...||::||::.:::... :...|..|||.:..|:.....||:|:||||
Mouse   223 TGFEFV-PKNEDALMNAVASIGPISVAIDARHASFLFYKRGIYYEPNCSSSVVTHSMLLVGYGFT 286

  Fly   377 --SEKGQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPVV 420
              ...|:.||:||||....||.|||.::.|.| |:|.||....||.|
Mouse   287 GRESDGRKYWLVKNSMGTQWGNKGYMKISRDKGNHCGIATYALYPRV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	13/51 (25%)
		Peptidase_C1A	204..418	CDD:239068	91/219 (42%)
Ctsm	NP_071721.2	Inhibitor_I29	29..87	CDD:214853	13/50 (26%)
		Peptidase_C1A	115..331	CDD:239068	91/219 (42%)