Protein Alignment CtsK2 and Cts8

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_062414.3
• Gene: Cts8 / 56094
• MGIID: 1860275
• Length: 333
• Species: Mus musculus
• Alignment Length: 309
• Identity: 122/309 - (39%)
• Similarity: 164/309 - (53%)
• Gaps: 22/309 - (7%)

  Fly   121 KTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEA 185
            |.| |..:.......:.....||:..|..:.||...|...||||.|:|..|:...||.:   |..
Mouse    38 KNY-SMEEEGQKRAVWEENMKLVKQHNIEYDQGKKNFTMDVNAFGDMTGEEYRKMLTDI---PVP 98

  Fly   186 KARAAASLKLVNLP-AKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPN 249
            ..|   ..|.::.| |..:|...|||:.|.|||||.||||.|||||:..|||||..|||||.|..
Mouse    99 NFR---KKKSIHQPIAGYLPKFVDWRKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKTGKLVP 160

  Fly   250 LSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQK--GVSQEGAYPYIDNKGTCKYDGSKSGA 312
            ||.||||||..:|  |..||   |:.:.|..:..|.|  |:..|..|||....|.|:|...:|.|
Mouse   161 LSTQNLVDCSRLE--GNFGC---FKGSTFLALKYVWKNRGLEAESTYPYKGTDGHCRYHPERSAA 220

  Fly   313 TLQGFAAIPPKDEEQLKKVVATLGPVACSVNGL-ETLKNYAGGIYNDDECNKGEPNHSILVVGYG 376
            .:..|:.: ...|:.|.:.|||:||::..::.. ::.:.|..|||.:.:|:....|||:||||||
Mouse   221 RITSFSFV-SNSEKDLMRAVATIGPISVGIDARHKSFRLYREGIYYEPKCSSNIINHSVLVVGYG 284

  Fly   377 SE----KGQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPVV 420
            .|    .|..||::|||..:.||..||.:|.||: |:|.||....||.|
Mouse   285 YEGKESDGNKYWLIKNSHGEQWGMNGYMKLARGRNNHCGIASYAVYPRV 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	15/50 (30%)
		Peptidase_C1A	204..418	CDD:239068	96/221 (43%)
Cts8	NP_062414.3	Inhibitor_I29	29..87	CDD:214853	15/49 (31%)
		Peptidase_C1A	115..331	CDD:239068	96/221 (43%)