Protein Alignment CtsK2 and ctsk

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001017778.1
• Gene: ctsk / 550475
• ZFINID: ZDB-GENE-001205-4
• Length: 333
• Species: Danio rerio
• Alignment Length: 302
• Identity: 116/302 - (38%)
• Similarity: 171/302 - (56%)
• Gaps: 24/302 - (7%)

  Fly   131 LHEGAFAST---KNL--VEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLK----RSPEAK 186
            |:|.:...|   ||:  :||.|..:..|:||:...:|.|.|:|..|...::.||:    |.|
Zfish    44 LNEESIRRTIWEKNMLFIEAHNKEYELGIHTYDLGMNHFGDMTLEEVAEKVMGLQMPMYRDP--- 105

  Fly   187 ARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLS 251
                |:..:.:.....:|.:.|:|:.|.||.||.||:|||||||::.||:||...:..|.|.:||
Zfish   106 ----ANTFVPDDRVGKLPKSIDYRKLGYVTSVKNQGSCGSCWAFSSVGALEGQLMKTKGQLVDLS 166

  Fly   252 EQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYDGSKSGATLQG 316
            .||||||....|    ||.||:...||.::...| |:..|.:|||:.....|.|:.|...|:.:|
Zfish   167 PQNLVDCVTEND----GCGGGYMTNAFRYVSNNQ-GIDSEESYPYVGTDQQCAYNTSGVAASCRG 226

  Fly   317 FAAIPPKDEEQLKKVVATLGPVACSVNGLE-TLKNYAGGIYNDDECNKGEPNHSILVVGYG-SEK 379
            :..||..:|..|...||.:|||:..::.:: |...|..|:|.|..|||.:.||::|.|||| :.:
Zfish   227 YKEIPQGNERALTAAVANVGPVSVGIDAMQSTFLYYKSGVYYDPNCNKEDVNHAVLAVGYGATPR 291

  Fly   380 GQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPVV 420
            |:.||||||||.:.||:|||..:.|.: |.|.||...|:||:
Zfish   292 GKKYWIVKNSWGEEWGKKGYVLMARNRNNACGIANLASFPVM 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	15/45 (33%)
		Peptidase_C1A	204..418	CDD:239068	93/216 (43%)
ctsk	NP_001017778.1	Inhibitor_I29	30..89	CDD:214853	15/44 (34%)
		Peptidase_C1	118..332	CDD:425470	93/218 (43%)