Protein Alignment CtsK2 and Ctsll3

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001395605.1
• Gene: Ctsll3 / 498691
• RGDID: 1560071
• Length: 330
• Species: Rattus norvegicus
• Alignment Length: 335
• Identity: 128/335 - (38%)
• Similarity: 188/335 - (56%)
• Gaps: 23/335 - (6%)

  Fly    93 VGNIAKAVPKVPLLSNVQDFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTF 157
            :|.|:.|....|....|.:  ::.::.|||| :..:.......:.:...::...|..:.:|.|.|
  Rat    12 LGMISAAPTHDPSFDTVWE--EWKTKHGKTY-NTNEEGQKRAVWENNMKMINLHNEDYLKGKHGF 73

  Fly   158 KQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKP----IPDAFDWREHGGVTPV 218
            ...:|||.|||::||...:||.:         ....|::.:..:|    :|...|||:||.||||
  Rat    74 SLEMNAFGDLTNTEFRELMTGFQ---------GQKTKMMKVFPEPFLGDVPKTVDWRKHGYVTPV 129

  Fly   219 KFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDE 283
            |.||.|||||||:..|::||..|||||.|..|||||||||.  ...|..|||||..:.||.::.:
  Rat   130 KNQGPCGSCWAFSAVGSLEGQVFRKTGKLVPLSEQNLVDCS--WSHGNKGCDGGLPDFAFQYVKD 192

  Fly   284 VQKGVSQEGAYPYIDNKGTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVN-GLET 347
             ..|:....:|||....|||:|:...|.|.:.||.:||| .|..|.|.|||:||::..:: ..::
  Rat   193 -NGGLDTSVSYPYEALNGTCRYNPKYSAAKVVGFMSIPP-SENALMKAVATVGPISVGIDIKHKS 255

  Fly   348 LKNYAGGIYNDDECNKGEPNHSILVVGYGSEK-GQDYWIVKNSWDDTWGEKGYFRLPRG-KNYCF 410
            .:.|.||:|.:.:|:....||::||||||.|. |:.||:|||||...||..||.::.:. .|.|.
  Rat   256 FQFYKGGMYYEPDCSSTNLNHAVLVVGYGEESDGRKYWLVKNSWGRDWGMDGYIKMAKDWNNNCG 320

  Fly   411 IAEECSYPVV 420
            ||.:.|||:|
  Rat   321 IASDASYPIV 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	14/59 (24%)
		Peptidase_C1A	204..418	CDD:239068	100/216 (46%)
Ctsll3	NP_001395605.1	Inhibitor_I29	29..87	CDD:214853	14/60 (23%)
		Peptidase_C1	114..329	CDD:425470	101/218 (46%)