Protein Alignment CtsK2 and Ctsrl1

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001017509.1
• Gene: Ctsrl1 / 498688
• RGDID: 1562210
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 331
• Identity: 116/331 - (35%)
• Similarity: 169/331 - (51%)
• Gaps: 29/331 - (8%)

  Fly   104 PLLSNVQD--FGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFAD 166
            |:|....|  :.::..:..|:| |..:..|....:.....:::..|.....|.:.|...:|.|.|
  Rat    19 PILDPSLDAEWQEWKKKYDKSY-SLEEEELRRAVWEENLKMIKLHNGENGLGKNGFTMEINEFGD 82

  Fly   167 LTHSEFLSQLT--GLKRSPEAKA---RAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGS 226
            .|..||...:.  .::...|.|:   |||.|:         .|...|||:.|.||||:.||.|.:
  Rat    83 TTGEEFRKMMVEFPVQTHREGKSIMKRAAGSI---------FPKFVDWRKKGYVTPVRRQGNCNA 138

  Fly   227 CWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQE 291
            ||||:.|||||..|..::|.|..||.||||||...:  |.|||.||....||.::.. ..|:..|
  Rat   139 CWAFSVTGAIEAQTIWQSGKLIPLSVQNLVDCSKPQ--GNNGCLGGDTYNAFQYVLH-NGGLQSE 200

  Fly   292 GAYPYIDNKGTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGL-ETLKNYAGGI 355
            ..|||....|.|:|:...|.|.:.||.:: |:.|:.|...|||:||::..::.. |:.|.|..||
  Rat   201 ATYPYEGKDGPCRYNPKNSSAEITGFVSL-PESEDILMVAVATIGPISAGIDASHESFKFYKKGI 264

  Fly   356 YNDDECNKGEPNHSILVVGYGSEKGQD-----YWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEE 414
            |::..|:.....|.:||||||. ||.|     ||::||||...||.:||.::.:.| |:|.||..
  Rat   265 YHEPNCSSNSVTHGVLVVGYGF-KGNDTGGDHYWLIKNSWGKQWGIRGYMKITKDKNNHCAIASY 328

  Fly   415 CSYPVV 420
            ..||.:
  Rat   329 AHYPTI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	11/59 (19%)
		Peptidase_C1A	204..418	CDD:239068	92/220 (42%)
Ctsrl1	NP_001017509.1	Inhibitor_I29	29..87	CDD:214853	11/58 (19%)
		Peptidase_C1A	116..332	CDD:239068	92/220 (42%)