Protein Alignment CtsK2 and ctss1

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: XP_017207692.2
• Gene: ctss1 / 393398
• ZFINID: ZDB-GENE-040426-1583
• Length: 375
• Species: Danio rerio
• Alignment Length: 308
• Identity: 118/308 - (38%)
• Similarity: 166/308 - (53%)
• Gaps: 15/308 - (4%)

  Fly   117 SQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKR 181
            ||..|||.:..:..|....:......:...|.|.|.|:|::...:|..:|:|..| ::.:.||..
Zfish    79 SQHNKTYRNTREERLRRSVWKQNLQDILLHNEAAAVGLHSYTLGLNQLSDMTADE-VNDMNGLLE 142

  Fly   182 S--PEAKAR-AAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRK 243
            .  |:..|. :..||       :.:|...:|.|||.|:||:.||.|||||||:..|::|....|:
Zfish   143 EDFPDVNATFSPPSL-------QTLPQRVNWTEHGMVSPVQNQGPCGSCWAFSAVGSLEAQMKRR 200

  Fly   244 TGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYDGS 308
            |.:|..||.|||:||.  ...|..||.|||...||.::.: .:|:.....|||...:|.|:|..|
Zfish   201 TAALVPLSAQNLLDCS--VSLGNRGCKGGFLSRAFLYVIQ-NRGIDSSTFYPYEHKEGVCRYSVS 262

  Fly   309 KSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNG-LETLKNYAGGIYNDDECNKGEPNHSILV 372
            .......||..:|..:|..|:..||.:|||:..:|. |.:...|..|||||.:|:....||::||
Zfish   263 GRAGYCTGFRIVPRHNEAALQSAVANIGPVSVGINAKLLSFHRYRSGIYNDPKCSSALINHAVLV 327

  Fly   373 VGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEECSYPVV 420
            ||||||.|||||:|||||...|||.||.|:.|.||.|.|:....||.:
Zfish   328 VGYGSENGQDYWLVKNSWGTAWGENGYIRMARNKNMCGISSFGIYPTI 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	14/54 (26%)
		Peptidase_C1A	204..418	CDD:239068	95/214 (44%)
ctss1	XP_017207692.2	Inhibitor_I29	74..133	CDD:214853	14/53 (26%)
		Peptidase_C1A	161..373	CDD:239068	95/214 (44%)