Protein Alignment CtsK2 and Ctsw

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001019413.1
• Gene: Ctsw / 293676
• RGDID: 1309354
• Length: 371
• Species: Rattus norvegicus
• Alignment Length: 343
• Identity: 108/343 - (31%)
• Similarity: 158/343 - (46%)
• Gaps: 69/343 - (20%)

  Fly   115 FLSQSGKTYLSAADRALHEGAFASTKNLVEA--------GNAAFAQGVHTFKQAVNAFADLTHSE 171
            |..|..::|.:.|:.....|.||  .||.:|        |.|.|.|         ..|:|||..|
  Rat    43 FQIQFNRSYSNPAEYTRRLGIFA--HNLAQAQRLQEEDLGTAEFGQ---------TPFSDLTEEE 96

  Fly   172 FLSQLTGLKRSPEAKARAAASLKLVNLPAK--------PIPDAFDWRE-HGGVTPVKFQGTCGSC 227
            | .||.|.:|:||         :::|:..|        .:|...|||: ...::.:|.||.|..|
  Rat    97 F-GQLYGHQRAPE---------RILNMAKKVKSERWGESVPPTCDWRKVKNIISSIKNQGNCRCC 151

  Fly   228 WAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEG 292
            ||.|....|:.....||....::|.|.|:||    |...|||:|||...|:..:.. ..|::.|.
  Rat   152 WAIAAADNIQTLWRIKTQQFVDVSVQELLDC----DRCGNGCNGGFVWDAYITVLN-NSGLASEE 211

  Fly   293 AYPYIDNK--GTCKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGI 355
            .||:..::  ..|..|..:..|.:|.|..: ..:|:.:...:|..||:..::| ::.|:.|..|:
  Rat   212 DYPFQGHQKPHRCLADKYRKVAWIQDFTML-SSNEQVIAGYLAIHGPITVTIN-MKLLQYYQKGV 274

  Fly   356 Y--NDDECNKGEPNHSILVVGYGSEKG-----------------QDYWIVKNSWDDTWGEKGYFR 401
            .  ....|:....|||:|:||:|.|||                 ..|||:||||...||||||||
  Rat   275 IKATPSTCDPHLVNHSVLLVGFGKEKGGMQTGTLLSHSRKPRRSTPYWILKNSWGAEWGEKGYFR 339

  Fly   402 LPRGKNYCFIAEECSYPV 419
            |.||.|.|.||:   ||:
  Rat   340 LYRGNNTCGIAK---YPI 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	18/64 (28%)
		Peptidase_C1A	204..418	CDD:239068	78/235 (33%)
Ctsw	NP_001019413.1	Inhibitor_I29	40..96	CDD:214853	18/63 (29%)
		Peptidase_C1	126..356	CDD:425470	80/239 (33%)