Protein Alignment CtsK2 and Ctsr

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_783171.2
• Gene: Ctsr / 290975
• RGDID: 631422
• Length: 334
• Species: Rattus norvegicus
• Alignment Length: 319
• Identity: 112/319 - (35%)
• Similarity: 167/319 - (52%)
• Gaps: 21/319 - (6%)

  Fly   111 DFGDFLSQSGKTYLSAAD---RALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEF 172
            ::.|:.::..|:|....:   ||:.|    ....:::..|...:.|.:.|...:|.|.|||..||
  Rat    28 EWHDWKTEYEKSYTMEEEGHRRAVWE----ENMKMIKLHNRENSLGKNGFIMEMNEFGDLTAEEF 88

  Fly   173 LSQLTGLKRSPEAKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIE 237
            ...:..:......|.:......:.|:    :|...|||:.|.||.|:.|..|.||||||.|||||
  Rat    89 RKMMVNIPIRSHRKGKIIRKRDVGNV----LPKFVDWRKKGYVTRVQNQKFCNSCWAFAVTGAIE 149

  Fly   238 GHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGT 302
            |..|.|||.|..||.||||||  .:..|..||..|....|:.::.. ..|:..|..|||...:|.
  Rat   150 GQMFNKTGQLTPLSVQNLVDC--TKSQGNEGCQWGDPHIAYEYVLN-NGGLEAEATYPYKGKEGV 211

  Fly   303 CKYDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVN-GLETLKNYAGGIYNDDECNKGEP 366
            |:|:...|.|.:.||.:: |:.|:.|.:.|||:||::.:|: ...:...|..|:|::..|:....
  Rat   212 CRYNPKHSKAEITGFVSL-PESEDILMEAVATIGPISVAVDASFNSFGFYKKGLYDEPNCSNNTV 275

  Fly   367 NHSILVVGYGSE----KGQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPVV 420
            |||:||||||.|    .|..||::||||...||.:||.::|:.: |:|.||....||.|
  Rat   276 NHSVLVVGYGFEGNETDGNSYWLIKNSWGRKWGLRGYMKIPKDQNNFCAIASYAHYPTV 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	14/62 (23%)
		Peptidase_C1A	204..418	CDD:239068	91/219 (42%)
Ctsr	NP_783171.2	Inhibitor_I29	29..87	CDD:214853	14/61 (23%)
		Peptidase_C1A	116..332	CDD:239068	91/219 (42%)