DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4847 and cpr-6

DIOPT Version :9

Sequence 1:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_741818.1	Gene:	cpr-6 / 180931	WormBaseID:	WBGene00000786	Length:	379	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	75/253 - (29%)
Similarity:	112/253 - (44%)	Gaps:	53/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 IPDAFD----WREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFR----KTGSLP-NLSEQNLVDC 258
            ||::||    |.:...:..::.|.:|||||||   ||:|..:.|    ..|.|. .||..:|:.|
Worm   105 IPESFDSRDNWPKCDSIKVIRDQSSCGSCWAF---GAVEAMSDRICIASHGELQVTLSADDLLSC 166

  Fly   259 GPVEDFGLNGCDGGFQEAAFCFIDEVQKGV-------SQEGAYPY-------------------- 296
            .....|   ||:||...||:.:  .|:.|:       :..|..||
Worm   167 CKSCGF---GCNGGDPLAAWRY--WVKDGIVTGSNYTANNGCKPYPFPPCEHHSKKTHFDPCPHD 226

  Fly   297 ------IDNKGTCKY-DGSKSGATLQGFAAIPPKDE-EQLKKVVATLGPVACSVNGLETLKNYAG 353
                  .:.|....| |.:.|.....|.:|...||: |.::|.:.|.||:..:....|...||.|
Worm   227 LYPTPKCEKKCVSDYTDKTYSEDKFFGASAYGVKDDVEAIQKELMTHGPLEIAFEVYEDFLNYDG 291

  Fly   354 GIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFI 411
            |:|.......| ..|::.::|:|.:.|..||.|.|||:..|||.|:||:.||.:.|.|
Worm   292 GVYVHTGGKLG-GGHAVKLIGWGIDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGI 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	74/252 (29%)
cpr-6	NP_741818.1	Propeptide_C1	44..82	CDD:369701
cpr-6	NP_741818.1	Peptidase_C1A_CathepsinB	106..355	CDD:239111	74/252 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920