Protein Alignment CtsK2 and F32H5.1

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_506310.1
• Gene: F32H5.1 / 179815
• WormBaseID: WBGene00009347
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 284
• Identity: 68/284 - (23%)
• Similarity: 99/284 - (34%)
• Gaps: 74/284 - (26%)

  Fly   179 LKRSPEAKARAAASLKLVNLPAKPIPDAFD----WREHGGVTPVKFQGTCGSCWAFATTGAIEGH 239
            :|.:.|...:......||:     ||.:||    |.....:..|:.|..|||.   |...|:|..
 Worm    73 IKSNDEVSEKTGNDNVLVD-----IPSSFDSRQKWPSCSQIGAVRDQSDCGSA---AHLVAVEIA 129

  Fly   240 TFRK------TGSLPNLSEQNLVDC--GPVEDFGLN-GCDGG--------FQEAAFC----FIDE 283
            :.|.      |.:.| ||.|:.:.|  |.:...|.. ||||.        :|....|    :.|
 Worm   130 SDRTCIASNGTFNWP-LSAQDPLSCCVGLMSICGDGWGCDGSWPKDILKWWQTHGLCTGGNYND- 192

  Fly   284 VQKGVSQEGAYPYIDNKGTCKYDGSKSGATLQGFAAIPPKDEEQL-------------------- 328
                  |.|..||.......||....:.....|:..  |..||..
 Worm   193 ------QFGCKPYSIYPCDKKYANGTTSVPCPGYHT--PTCEEHCTSNITWPIAYKQDKHFGKAH 249

  Fly   329 ----KKV------VATLGPVACSVNGLETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDY 383
                ||:      :.|.|||..|....:...:|..|||.....:: |......::|:|.:.|..|
 Worm   250 YNVGKKMTDIQIEIMTNGPVIASFIIYDDFWDYKTGIYVHTAGDQ-EGGMDTKIIGWGVDNGVPY 313

  Fly   384 WIVKNSWDDTWGEKGYFRLPRGKN 407
            |:..:.|...:||.|:.|..||.|
 Worm   314 WLCVHQWGTDFGENGFVRFLRGVN 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410
		Peptidase_C1A	204..418	CDD:239068	63/259 (24%)
F32H5.1	NP_506310.1	Peptidase_C1A_CathepsinB	93..348	CDD:239111	63/259 (24%)