DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4847 and cpr-4

DIOPT Version :9

Sequence 1:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_504682.1	Gene:	cpr-4 / 179053	WormBaseID:	WBGene00000784	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	70/253 - (27%)
Similarity:	104/253 - (41%)	Gaps:	53/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 IPDAFD----WREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPN--LSEQNLVDCGPV 261
            ||..||    |.....:..::.|..||||||||...|........:....|  ||.::::.|  .
Worm    81 IPATFDARTQWPNCMSINNIRDQSDCGSCWAFAAAEAASDRFCIASNGAVNTLLSAEDVLSC--C 143

  Fly   262 EDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAY-------PY--------IDNK--GTCKYDGSK 309
            .:.|. ||:||:...|:.::  |:.|....|:|       ||        :.|.  .:|..||..
Worm   144 SNCGY-GCEGGYPINAWKYL--VKSGFCTGGSYEAQFGCKPYSLAPCGETVGNVTWPSCPDDGYD 205

  Fly   310 SGATLQ------------------GFAAIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIY 356
            :.|.:.                  ..|....|...|::..:...|||..:....|....|..|:|
Worm   206 TPACVNKCTNKNYNVAYTADKHFGSTAYAVGKKVSQIQAEIIAHGPVEAAFTVYEDFYQYKTGVY 270

  Fly   357 ---NDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFI 411
               ...|..    .|:|.::|:|::.|..||:|.|||:..|||.||||:.||.|.|.|
Worm   271 VHTTGQELG----GHAIRILGWGTDNGTPYWLVANSWNVNWGENGYFRIIRGTNECGI 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	69/252 (27%)
cpr-4	NP_504682.1	Peptidase_C1A_CathepsinB	82..331	CDD:239111	69/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820