DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4847 and cpz-1

DIOPT Version :9

Sequence 1:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_491023.2	Gene:	cpz-1 / 171829	WormBaseID:	WBGene00000788	Length:	306	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	73/264 - (27%)
Similarity:	112/264 - (42%)	Gaps:	62/264 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 AKPIPDAFDWREHGGVTPVKFQGT------CGSCWAFATTGAIEGH-TFRKTGSLPN--LSEQNL 255
            ::.:|..:|||:..|:........      |||||||..|.|:... ..::..:.|.  ||.|.:
Worm    62 SEDLPKTWDWRDANGINYASADRNQHIPQYCGSCWAFGATSALADRINIKRKNAWPQAYLSVQEV 126

  Fly   256 VDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCK---------------- 304
            :||.......:.|..||..:.|.      :.|:..|....|....|.|.
Worm   127 IDCSGAGTCVMGGEPGGVYKYAH------EHGIPHETCNNYQARDGKCDPYNRCGSCWPGECFSI 185

  Fly   305 -----YDGSKSGATLQGFAAIPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIYND--DECN 362
                 |..|:.| |:.|:        |::|..:...||:||.:...:..:.||||||.:  ||
Worm   186 KNYTLYKVSEYG-TVHGY--------EKMKAEIYHKGPIACGIAATKAFETYAGGIYKEVTDE-- 239

  Fly   363 KGEPNHSILVVGYG--SEKGQDYWIVKNSWDDTWGEKGYFRL------PRGKNYCF-IAEECSY- 417
              :.:|.|.|.|:|  .|.|.:|||.:|||.:.|||.|:|::      ..|..|.. |.|:|.:
Worm   240 --DIDHIISVHGWGVDHESGVEYWIGRNSWGEPWGEHGWFKIVTSQYKNAGSKYNLKIEEDCVWA 302

  Fly   418 -PVV 420
             |:|
Worm   303 DPIV 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	71/256 (28%)
cpz-1	NP_491023.2	Peptidase_C1A_CathepsinX	65..305	CDD:239149	71/258 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820