Protein Alignment CG4847 and CTSW

DIOPT Version :9

• Sequence 1: NP_725686.1
• Gene: CG4847 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001326.3
• Gene: CTSW / 1521
• HGNCID: 2546
• Length: 376
• Species: Homo sapiens
• Alignment Length: 376
• Identity: 113/376 - (30%)
• Similarity: 161/376 - (42%)
• Gaps: 81/376 - (21%)

  Fly    85 VAGAVQNAVGNIAKAVPKVPLLSNVQDFGD-----------FLSQSGKTYLSAADRALHEGAFAS 138
            |||..|...|         ||  ..||.|.           |..|..::|||..:.|.....||
Human    15 VAGLAQGIRG---------PL--RAQDLGPQPLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFA- 67

  Fly   139 TKNLVEA--------GNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKL 195
             .||.:|        |.|.|         .|..|:|||..|| .||.|.:|:..........::.
Human    68 -HNLAQAQRLQEEDLGTAEF---------GVTPFSDLTEEEF-GQLYGYRRAAGGVPSMGREIRS 121

  Fly   196 VNLPAKPIPDAFDWRE-HGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCG 259
            .. |.:.:|.:.|||: ...::|:|.|..|..|||.|..|.||...........::|.|.|:|||
Human   122 EE-PEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCG 185

  Fly   260 PVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKG-----TCKYDGSKSGATLQGFAA 319
            ...|    ||.|||...||..:.. ..|::.|..||:   :|     .|.....:..|.:|.|..
Human   186 RCGD----GCHGGFVWDAFITVLN-NSGLASEKDYPF---QGKVRAHRCHPKKYQKVAWIQDFIM 242

  Fly   320 IPPKDEEQLKKVVATLGPVACSVNGLETLKNYAGGIY--NDDECNKGEPNHSILVVGYGSEKGQD 382
            : ..:|.::.:.:||.||:..::| ::.|:.|..|:.  ....|:....:||:|:||:||.|.::
Human   243 L-QNNEHRIAQYLATYGPITVTIN-MKPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEE 305

  Fly   383 --------------------YWIVKNSWDDTWGEKGYFRLPRGKNYCFIAE 413
                                |||:||||...|||||||||.||.|.|.|.:
Human   306 GIWAETVSSQSQPQPPHPTPYWILKNSWGAQWGEKGYFRLHRGSNTCGITK 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	20/78 (26%)
		Peptidase_C1A	204..418	CDD:239068	77/238 (32%)
CTSW	NP_001326.3	Inhibitor_I29	42..98	CDD:214853	19/66 (29%)
		Peptidase_C1A	129..358	CDD:239068	77/238 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810