Protein Alignment CG4847 and CTSO

DIOPT Version :9

• Sequence 1: NP_725686.1
• Gene: CG4847 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_001325.1
• Gene: CTSO / 1519
• HGNCID: 2542
• Length: 321
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 102/323 - (31%)
• Similarity: 163/323 - (50%)
• Gaps: 13/323 - (4%)

  Fly    98 KAVPKVPLLSNV--QDFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQA 160
            :|:|.:|.|..:  :..||..|::..|......|.....||..:.|.....|:.|.....|....
Human     4 RALPWLPWLLWLLCRGGGDADSRAPFTPTWPRSREREAAAFRESLNRHRYLNSLFPSENSTAFYG 68

  Fly   161 VNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCG 225
            :|.|:.|...||  :...|:..|....|.:|.:.: ::|...:|..||||:...||.|:.|..||
Human    69 INQFSYLFPEEF--KAIYLRSKPSKFPRYSAEVHM-SIPNVSLPLRFDWRDKQVVTQVRNQQMCG 130

  Fly   226 SCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQ 290
            .||||:..||:|.....|...|.:||.|.::||    .:...||:||....|..:::::|..:.:
Human   131 GCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDC----SYNNYGCNGGSTLNALNWLNKMQVKLVK 191

  Fly   291 EGAYPYIDNKGTCKY-DGSKSGATLQGFAAIPPKD-EEQLKKVVATLGPVACSVNGLETLKNYAG 353
            :..||:....|.|.| .||.||.:::|::|....| |:::.|.:.|.||:...|:.: :.::|.|
Human   192 DSEYPFKAQNGLCHYFSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLVVIVDAV-SWQDYLG 255

  Fly   354 GIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPRGKNYCFIAEECS 416
            ||. ...|:.||.||::|:.|:.......||||:|||..:||..||..:..|.|.|.||:..|
Human   256 GII-QHHCSSGEANHAVLITGFDKTGSTPYWIVRNSWGSSWGVDGYAHVKMGSNVCGIADSVS 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	14/59 (24%)
		Peptidase_C1A	204..418	CDD:239068	77/215 (36%)
CTSO	NP_001325.1	Peptidase_C1A	109..319	CDD:239068	77/215 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5966
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.770