Protein Alignment CtsK2 and LOC1274676

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: XP_313831.5
• Gene: LOC1274676 / 1274676
• VectorBaseID: AGAMI1_007012
• Length: 375
• Species: Anopheles gambiae
• Alignment Length: 394
• Identity: 94/394 - (23%)
• Similarity: 146/394 - (37%)
• Gaps: 105/394 - (26%)

  Fly    71 GGLGNNRVGGALQNVAGAVQNAVGNIAKAVPKVPLLSNVQDFGDFLSQSGKTYLSAADRALHEGA 135
            |.||           .|:.:|.:|  .|.|.|    ::|:|     :|....|   .|.|.:...
Mosquito    16 GSLG-----------TGSAENQLG--LKLVVK----TSVED-----TQPQNYY---RDSASYGSR 55

  Fly   136 FASTKNL-----------VEAGNAAFAQGVH----TFKQAVNAFADLTHSEFLSQLTGLKRSPEA 185
            ||.:.:.           |....|||.:.::    |:|..||...:..:.      ||:......
Mosquito    56 FADSSSFAPEFFRTGYGNVLTSQAAFVEAINNRSTTWKAGVNPQRNDQYR------TGVLSDESM 114

  Fly   186 KARAAASLKLVNLPAKPIPDAFDWREHGGVTP----VKFQGTCGSCWAFATTGAI--------EG 238
            |.:..... ::....:|:|.:||.|:.....|    |:.||.|.|.:|.|....:        ||
Mosquito   115 KFQLPLGF-VLKKDEQPLPMSFDARQKWSYCPSMNMVRNQGCCDSSYAVAAVSTMTDRWCVHSEG 178

  Fly   239 HTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGA---------Y 294
            ......|:...||..:  .||       .|||||...|.:.:  .|:.|::..||         |
Mosquito   179 KAQFNFGAYDVLSCCH--RCG-------FGCDGGVPSAVWHY--WVENGITSGGAFGSHEGCQSY 232

  Fly   295 PYIDNKGTCKYDGSKSGA------TLQGF-------------AAIPPKDEEQLKKVVATLGPVAC 340
            |:    ..||..|..:..      ...|:             |...|||||::...|...||...
Mosquito   233 PF----DVCKKSGDSNDTPRCLRFCQPGYNVTYPEDKHYGRVAYTVPKDEERIMYEVFNFGPAQA 293

  Fly   341 SVNGLETLKNYAGGIYNDD-ECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYFRLPR 404
            :.........|..|:|... ....|  .||:.|:|:|.|....||:..|||...||:.|:|::.|
Mosquito   294 TFTMYTDFVQYKSGVYRHTFGVRVG--THSVKVMGWGVENDVKYWLCANSWGAQWGDGGFFKIVR 356

  Fly   405 GKNY 408
            |:::
Mosquito   357 GEDH 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	14/74 (19%)
		Peptidase_C1A	204..418	CDD:239068	65/246 (26%)
LOC1274676	XP_313831.5	Propeptide_C1	81..>97	CDD:462365	3/15 (20%)
		Peptidase_C1A_CathepsinB	132..370	CDD:239111	65/246 (26%)