Protein Alignment CtsK2 and Cts3

DIOPT Version :10

• Sequence 1: NP_725686.1
• Gene: CtsK2 / 36973
• FlyBaseID: FBgn0034229
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_081182.2
• Gene: Cts3 / 117066
• MGIID: 2151929
• Length: 332
• Species: Mus musculus
• Alignment Length: 308
• Identity: 113/308 - (36%)
• Similarity: 161/308 - (52%)
• Gaps: 24/308 - (7%)

  Fly   120 GKTYLSAADRALHEGAFASTKNLVEAGNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPE 184
            |||| |..:.......:......::..|.....|.|.|...:|||.|:|..||..::..:.....
Mouse    37 GKTY-SLEEEGQKRAVWEENMKKIKLHNGENGLGKHGFTMEMNAFGDMTLEEFRKEMIEIPVPTV 100

  Fly   185 AKARAAASLKLVNLPAKPIPDAFDWREHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPN 249
            .|.::......|||     |...:|::.|.||||:.|..|.||||.:.||||||..|||||.|..
Mouse   101 KKGKSVQKRLSVNL-----PKFINWKKRGYVTPVRTQIACNSCWAISVTGAIEGQMFRKTGQLIP 160

  Fly   250 LSEQNLVDCGPVEDFGLNGCDGGFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYDGSKSGATL 314
            ||.||||||  |:.   :||..|....:|.::.| :.|:..|..|||.|.:|:|:|:...|.|::
Mouse   161 LSVQNLVDC--VDG---SGCHAGSVLDSFKYLME-KGGLESEATYPYEDKQGSCRYNPENSTASI 219

  Fly   315 QGFAAIPPKDEEQLKKVVATLGPVACSVNGL-ETLKNYAGGIYNDDECNKG--EPNHSILVVGYG 376
            .||..| |.:|..|...||:|||::..::.. |:...|..|||.:..||..  ...|::|:||||
Mouse   220 TGFEFI-PNNEVDLMSAVASLGPISVVIDAWHESFLFYKRGIYYEPNCNNSLFALRHAVLLVGYG 283

  Fly   377 ----SEKGQDYWIVKNSWDDTWGEKGYFRLPRGK-NYCFIAEECSYPV 419
                ..:|:.|||:|||....||.|||.::.:.: |:|.||   |.||
Mouse   284 FIGRESEGRKYWIIKNSLGTKWGYKGYMKIAKDQGNHCGIA---SLPV 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsK2	NP_725686.1	Inhibitor_I29	112..172	CDD:462410	14/51 (27%)
		Peptidase_C1A	204..418	CDD:239068	91/221 (41%)
Cts3	NP_081182.2	Inhibitor_I29	29..87	CDD:214853	14/50 (28%)
		Peptidase_C1A	115..330	CDD:239068	93/224 (42%)