DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4847 and asic5

DIOPT Version :9

Sequence 1:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	XP_017951381.2	Gene:	asic5 / 100498195	XenbaseID:	XB-GENE-983430	Length:	852	Species:	Xenopus tropicalis

Alignment Length:	334	Identity:	99/334 - (29%)
Similarity:	153/334 - (45%)	Gaps:	47/334 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 GNIAKAVPKVPLLSNVQDFG-------DFLSQSGKTYLSAADRALHEGAFASTKNLVEAGNAAFA 151
            ||...|......|..:|.:|       ....:..:.:|.:.:|..:..|.|...||..|.:
Frog    55 GNFTSAPHSNAFLDFIQKYGRGYKDGSQVFQERYQIFLKSTERQNYLNAIALPTNLTSAAH---- 115

  Fly   152 QGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLVNLPAKP------IPDAFDWR 210
                   ..:|.|:||:..||.  .|.|:..|.....:       |.|.|.      :|..||||
Frog   116 -------YGINQFSDLSAEEFF--YTYLRSFPTGNYTS-------NKPFKNSAQQYFLPLRFDWR 164

  Fly   211 EHGGVTPVKFQGTCGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDGGFQE 275
            :...|||||.|.:||:||||:..||:|.....|..:|..||.|.::||..::    :||:||...
Frog   165 DKKLVTPVKNQLSCGACWAFSVVGAVESAYAIKWHTLEELSVQQVIDCSYLD----SGCNGGSTN 225

  Fly   276 AAFCFIDEVQKGVSQEGAYPYIDNKGTCKY-DGSKSGATLQGFAAIPPKD----EEQLKKVVATL 335
            .|..::.:.:..:.:...|.:....|.|.| ..:..|.::.|:..   :|    |:.:.|::..|
Frog   226 GALKWLYQTKTKLVRASEYNFKAKTGLCHYFPKTDFGVSINGYET---QDFSGTEDAMMKMLVDL 287

  Fly   336 GPVACSVNGLETLKNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDTWGEKGYF 400
            ||:...||.: :.::|.|||. ...|:.|.|||::||:||.......||||||||...||..||.
Frog   288 GPMVVIVNAV-SWQDYLGGII-QHHCSSGAPNHAVLVIGYDKTGDTPYWIVKNSWGTAWGADGYV 350

  Fly   401 RLPRGKNYC 409
            .:..|:|.|
Frog   351 YIKMGENIC 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	12/66 (18%)
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	74/211 (35%)
asic5	XP_017951381.2	Inhibitor_I29	66..129	CDD:400519	14/73 (19%)
		Peptidase_C1A	158..360	CDD:239068	74/211 (35%)
		ASC	387..816	CDD:395688
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010