DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30103 and nt5e

DIOPT Version :9

Sequence 1:	NP_725682.2	Gene:	CG30103 / 36969	FlyBaseID:	FBgn0050103	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	XP_002933973.1	Gene:	nt5e / 100489347	XenbaseID:	XB-GENE-984211	Length:	578	Species:	Xenopus tropicalis

Alignment Length:	540	Identity:	194/540 - (35%)
Similarity:	298/540 - (55%)	Gaps:	36/540 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KFTLLHTNDMHSRFDPISDTGGRCKTVDDAMGICFGG----FGRVAEAVSAARNTATDPVIYLNG 86
            :.|:|||||:|:|.:..:...|:|....|    |:||    |.::.|..|..|:     |:.|:.
Frog    24 QLTILHTNDVHARVEQTNRDSGKCGDPQD----CYGGVARRFAKIEEIRSTHRH-----VLLLDA 79

  Fly    87 GDSFQGTSWFSVYRGKMVARMLNFLAPDAMALGVHELDDGTDA-LAEFLNTITFPMVSSNINLIN 150
            ||.:|||.||:.|:|...|..:|:|..||||||.||.|:|... |:.||..:.||::|:||.  :
Frog    80 GDQYQGTIWFNYYKGHEAAYFMNYLKYDAMALGNHEFDNGVSGLLSPFLQEVKFPILSANIK--S 142

  Fly   151 EPKLAENANLVTSL-----VITKGNRKIGIVGYIRPDTKERTQPSN----VIFKREVPAINKETK 206
            :.:||.|   :|..     ::..|..|||::||   .::|....||    ::|:.||.|:..:..
Frog   143 DKQLAPN---ITGYYLPYKILEVGTEKIGVIGY---SSRETPVLSNSGPHLVFEDEVLALQPQVD 201

  Fly   207 KLKGQGIDIIIALGHSGYEKDMEIAKRCPDVDIVVGGQSHTFLYSGKAPSKEVSEGPYPTIVVKP 271
            ||...|::.||||||||:|.|..||::...:|:||||.::||||:|..||.:|..|.||..|:..
Frog   202 KLLTLGVNKIIALGHSGFETDKLIAQKVKGIDVVVGGHTNTFLYTGPPPSNDVPVGEYPFSVMSD 266

  Fly   272 DGRKVPVVQAYAYTKYLGNLSLEFDNGGNLLSFKGSPILLNNRFHPRKDVQDFLQLYRQVIDDME 336
            |||.||||||||:.||||.|::.||..|.::...|:||||:........:...:..:::.|.:..
Frog   267 DGRSVPVVQAYAFGKYLGYLNITFDEQGTVVHSFGNPILLDRSIPEDATLLGEVNQWKEAIRNYS 331

  Fly   337 RHVVGTTSVYLNGDRKSCGYSECNFGNFIADSFVYARVVQTMADRSSWTDASIGLINAGAIRASI 401
            ...:|.|.|||||....|...|||.||.|.|:.:...:  ...|...|...|:.::|.|.|||:|
Frog   332 SQPIGKTLVYLNGSSLECRNRECNMGNLICDAMIDNNI--RHPDEVRWNHVSLCILNGGGIRAAI 394

  Fly   402 DPG-ETGAITEADVVTVLPFSQDLYYTRISGSQLMKALEHSAQMRSKHMTSAHLQVSGLRLKFNH 465
            |.. ..|.||..|:::||||........|.||.|..|.|||.. |....|...|||.|:::.|:.
Frog   395 DERISNGTITTEDLISVLPFEGTFDLIEIKGSTLKSAFEHSVH-RYGSGTGEFLQVGGIKVVFDT 458

  Fly   466 SLPKGERITEIRALCSDCQIPHYEAVDTNGYYGVVVTSFLLNGGEGYSFVDPKRPEVENMTILDR 530
            ....|:|:.::..:|::|::|.|..|:.:..|.||:.|::..||:|:|.:..:..:.::.. .|.
Frog   459 EKSPGQRVVKLEVICTECRVPKYVPVEMDKIYKVVLPSYIAAGGDGFSMLKDESLKHDSGD-TDL 522

  Fly   531 MAVIQYLQEHKVIYPEREDR 550
            ..|..|:.:.:.:||..|.|
Frog   523 TVVSNYIAQRQRVYPAVEGR 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30103	NP_725682.2	UshA	25..555	CDD:223808	194/540 (36%)
		MPP_CD73_N	27..311	CDD:277354	121/297 (41%)
		5_nucleotid_C	339..511	CDD:280945	61/172 (35%)
nt5e	XP_002933973.1	MPP_CD73_N	25..306	CDD:277354	121/297 (41%)
nt5e	XP_002933973.1	5_nucleotid_C	334..510	CDD:376948	63/178 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	163	1.000	Domainoid score	I3915
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1876
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D159192at33208
OrthoFinder	1	1.000	-	-		FOG0001036
OrthoInspector	1	1.000	-	-		otm47705
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1114
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060